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优化螺旋二极管阵列剂量计的准确性:一种综合校准方法,结合新颖的虚拟测斜仪。

Optimizing the accuracy of a helical diode array dosimeter: a comprehensive calibration methodology coupled with a novel virtual inclinometer.

机构信息

Sun Nuclear Corp., Melbourne, FL 32940, USA.

出版信息

Med Phys. 2011 Sep;38(9):5021-32. doi: 10.1118/1.3622823.

Abstract

PURPOSE

The goal of any dosimeter is to be as accurate as possible when measuring absolute dose to compare with calculated dose. This limits the uncertainties associated with the dosimeter itself and allows the task of dose QA to focus on detecting errors in the treatment planning (TPS) and/or delivery systems. This work introduces enhancements to the measurement accuracy of a 3D dosimeter comprised of a helical plane of diodes in a volumetric phantom.

METHODS

We describe the methods and derivations of new corrections that account for repetition rate dependence, intrinsic relative sensitivity per diode, field size dependence based on the dynamic field size determination, and positional correction. Required and described is an accurate "virtual inclinometer" algorithm. The system allows for calibrating the array directly against an ion chamber signal collected with high angular resolution. These enhancements are quantitatively validated using several strategies including ion chamber measurements taken using a "blank" plastic shell mimicking the actual phantom, and comparison to high resolution dose calculations for a variety of fields: static, simple arcs, and VMAT. A number of sophisticated treatment planning algorithms were benchmarked against ion chamber measurements for their ability to handle a large air cavity in the phantom.

RESULTS

Each calibration correction is quantified and presented vs its independent variable(s). The virtual inclinometer is validated by direct comparison to the gantry angle vs time data from machine log files. The effects of the calibration are quantified and improvements are seen in the dose agreement with the ion chamber reference measurements and with the TPS calculations. These improved agreements are a result of removing prior limitations and assumptions in the calibration methodology. Average gamma analysis passing rates for VMAT plans based on the AAPM TG-119 report are 98.4 and 93.3% for the 3%/3 mm and 2%/2 mm dose-error/distance to agreement threshold criteria, respectively, with the global dose-error normalization. With the local dose-error normalization, the average passing rates are reduced to 94.6 and 85.7% for the 3%/3 mm and 2%/2 mm criteria, respectively. Some algorithms in the convolution/superposition family are not sufficiently accurate in predicting the exit dose in the presence of a 15 cm diameter air cavity.

CONCLUSIONS

Introduction of the improved calibration methodology, enabled by a robust virtual inclinometer algorithm, improves the accuracy of the dosimeter's absolute dose measurements. With our treatment planning and delivery chain, gamma analysis passing rates for the VMAT plans based on the AAPM TG-119 report are expected to be above 91% and average at about 95% level for γ(3%/3 mm) with the local dose-error normalization. This stringent comparison methodology is more indicative of the true VMAT system commissioning accuracy compared to the often quoted dose-error normalization to a single high value.

摘要

目的

任何剂量仪的目标都是在测量绝对剂量时尽可能准确,以便与计算剂量进行比较。这限制了剂量仪本身的不确定性,并使剂量 QA 任务能够专注于检测治疗计划(TPS)和/或输送系统中的错误。这项工作介绍了对由体模中螺旋平面二极管组成的 3D 剂量仪的测量精度的改进。

方法

我们描述了新校正方法和推导,这些校正方法考虑了重复率依赖性、每个二极管的固有相对灵敏度、基于动态场尺寸确定的场尺寸依赖性以及位置校正。需要并描述了一个准确的“虚拟倾斜计”算法。该系统允许使用高角分辨率收集的离子室信号直接对数组进行校准。使用几种策略对这些增强功能进行了定量验证,包括使用模拟实际体模的空塑料外壳进行的离子室测量,以及与各种场的高分辨率剂量计算进行比较:静态、简单弧形和 VMAT。许多复杂的治疗计划算法已针对其在体模中处理大空腔的能力与离子室测量进行了基准测试。

结果

每个校准校正都针对其独立变量进行了量化和呈现。虚拟倾斜计通过与机器日志文件中的旋转架角度与时间数据进行直接比较进行了验证。校正的效果已量化,并在与离子室参考测量值和 TPS 计算值的剂量一致性方面看到了改进。这些改进的一致性是由于在校准方法中消除了先前的限制和假设。基于 AAPM TG-119 报告,VMAT 计划的平均伽马分析通过率分别为 98.4%和 93.3%,适用于 3%/3mm 和 2%/2mm 剂量误差/距离符合标准,采用全局剂量误差归一化。使用局部剂量误差归一化,3%/3mm 和 2%/2mm 标准的平均通过率分别降低至 94.6%和 85.7%。在存在 15cm 直径空腔的情况下,卷积/叠加族中的某些算法在预测出口剂量方面不够准确。

结论

通过稳健的虚拟倾斜计算法引入改进的校准方法,提高了剂量仪绝对剂量测量的准确性。使用我们的治疗计划和输送链,基于 AAPM TG-119 报告的 VMAT 计划的伽马分析通过率预计将高于 91%,并且在使用局部剂量误差归一化时,平均在 95%左右的γ(3%/3mm)水平。与通常引用的归一化为单个高值的剂量误差相比,这种严格的比较方法更能指示真实的 VMAT 系统调试精度。

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