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使用平面电离室阵列和圆柱形二极管阵列对颅外治疗进行机器人放射外科系统特定患者质量保证。

Robotic radiosurgery system patient-specific QA for extracranial treatments using the planar ion chamber array and the cylindrical diode array.

作者信息

Lin Mu-Han, Veltchev Iavor, Koren Sion, Ma Charlie, Li Jinsgeng

机构信息

University of Maryland School of Medicine.

出版信息

J Appl Clin Med Phys. 2015 Jul 8;16(4):290–305. doi: 10.1120/jacmp.v16i4.5486.

Abstract

Robotic radiosurgery system has been increasingly employed for extracranial treatments. This work is aimed to study the feasibility of a cylindrical diode array and a planar ion chamber array for patient-specific QA with this robotic radiosurgery system and compare their performance. Fiducial markers were implanted in both systems to enable image-based setup. An in-house program was developed to postprocess the movie file of the measurements and apply the beam-by-beam angular corrections for both systems. The impact of noncoplanar delivery was then assessed by evaluating the angles created by the incident beams with respect to the two detector arrangements and cross-comparing the planned dose distribution to the measured ones with/without the angular corrections. The sensitivity of detecting the translational (1-3 mm) and the rotational (1°-3°) delivery errors were also evaluated for both systems. Six extracranial patient plans (PTV 7-137 cm³) were measured with these two systems and compared with the calculated doses. The plan dose distributions were calculated with ray-tracing and the Monte Carlo (MC) method, respectively. With 0.8 by 0.8 mm² diodes, the output factors measured with the cylindrical diode array agree better with the commissioning data. The maximum angular correction for a given beam is 8.2% for the planar ion chamber array and 2.4% for the cylindrical diode array. The two systems demonstrate a comparable sensitivity of detecting the translational targeting errors, while the cylindrical diode array is more sensitive to the rotational targeting error. The MC method is necessary for dose calculations in the cylindrical diode array phantom because the ray-tracing algorithm fails to handle the high-Z diodes and the acrylic phantom. For all the patient plans, the cylindrical diode array/ planar ion chamber array demonstrate 100% / > 92% (3%/3 mm) and > 96% / ~ 80% (2%/2 mm) passing rates. The feasibility of using both systems for robotic radiosurgery system patient-specific QA has been demonstrated. For gamma evaluation, 2%/2 mm criteria for cylindrical diode array and 3%/3 mm criteria for planar ion chamber array are suggested. The customized angular correction is necessary as proven by the improved passing rate, especially with the planar ion chamber array system.

摘要

机器人放射外科系统已越来越多地用于颅外治疗。这项工作旨在研究圆柱形二极管阵列和平面电离室阵列用于该机器人放射外科系统患者特定质量保证(QA)的可行性,并比较它们的性能。在两个系统中均植入了基准标记,以实现基于图像的设置。开发了一个内部程序来对测量的电影文件进行后处理,并对两个系统进行逐束角度校正。然后,通过评估入射光束相对于两种探测器布置所形成的角度,并将计划剂量分布与经过/未经过角度校正的测量剂量分布进行交叉比较,来评估非共面照射的影响。还评估了两个系统检测平移(1 - 3毫米)和旋转(1° - 3°)照射误差的灵敏度。使用这两个系统对六个颅外患者计划(PTV 7 - 137立方厘米)进行了测量,并与计算剂量进行了比较。计划剂量分布分别用射线追踪法和蒙特卡罗(MC)方法计算。对于0.8×0.8平方毫米的二极管,用圆柱形二极管阵列测量的输出因子与调试数据的一致性更好。对于给定光束,平面电离室阵列的最大角度校正为8.2%,圆柱形二极管阵列为2.4%。两个系统在检测平移靶向误差方面表现出可比的灵敏度,而圆柱形二极管阵列对旋转靶向误差更敏感。在圆柱形二极管阵列体模中进行剂量计算时,蒙特卡罗方法是必要的,因为射线追踪算法无法处理高原子序数的二极管和丙烯酸体模。对于所有患者计划,圆柱形二极管阵列/平面电离室阵列的通过率分别为100% / > 92%(3%/3毫米)和> 96% / ~ 80%(2%/2毫米)。已证明使用这两个系统进行机器人放射外科系统患者特定QA的可行性。对于伽马评估,建议圆柱形二极管阵列采用2%/2毫米标准,平面电离室阵列采用3%/3毫米标准。如通过提高通过率所证明的,定制角度校正是必要的,特别是对于平面电离室阵列系统。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/eeb7/5690014/a13217856c63/ACM2-16-290-g006.jpg

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