职业性鼻炎。

Occupational rhinitis.

机构信息

Division of Immunology, Allergy and Rheumatology, University of Cincinnati College of Medicine, 3255 Eden Avenue, Cincinnati, OH 45267-0563, USA.

出版信息

Immunol Allergy Clin North Am. 2011 Nov;31(4):787-96, vii. doi: 10.1016/j.iac.2011.07.007.

DOI:10.1016/j.iac.2011.07.007

PMID:21978857

Abstract

Work-related rhinitis, which includes work-exacerbated rhinitis and occupational rhinoconjunctivitis (OR), is two to three times more common than occupational asthma. High molecular weight proteins and low molecular weight chemicals have been implicated as causes of OR. The diagnosis of work-related rhinitis is established based on occupational history and documentation of immunoglobulin E (IgE) mediated sensitization to the causative agent if possible. Management of work-related rhinitis is similar to that of other causes of rhinitis and includes elimination or reduction of exposure to causative agents combined with pharmacotherapy. If allergens are commercially available, allergen immunotherapy can be considered.

摘要

职业性鼻炎，包括工作加重性鼻炎和职业性鼻结膜炎（OR），比职业性哮喘更为常见两到三倍。高分子量蛋白和低分子量化学物质已被认为是 OR 的原因。职业性鼻炎的诊断基于职业史和如果可能的话对致敏原的免疫球蛋白 E（IgE）介导敏感化的记录。职业性鼻炎的治疗与其他原因的鼻炎相似，包括消除或减少接触致病物，并结合药物治疗。如果过敏原是商业上可获得的，可以考虑过敏原免疫疗法。