Division of Immunology/Allergy Section, Department of Internal Medicine, University of Cincinnati College of Medicine, 231 Albert Sabin Way, ML #563, Cincinnati, OH 45267-0563, USA.
Curr Allergy Asthma Rep. 2010 Mar;10(2):99-104. doi: 10.1007/s11882-010-0094-2.
Work-related rhinitis, which includes work-exacerbated rhinitis and occupational rhinitis, may be two to three times more common than occupational asthma. Both high molecular weight proteins and low molecular weight chemicals have been implicated as causes of occupational rhinitis. A diagnosis is established based on occupational history and, if appropriate, documentation of IgE-mediated sensitization to the causative agent. Management of work-related rhinitis is similar to that of non-work-related rhinitis and includes elimination or reduction of exposure to offending agents combined with pharmacotherapy. If treatment allergens are commercially available, allergen immunotherapy may also be considered if appropriate.
职业性鼻炎(包括工作加剧性鼻炎和职业性鼻炎)可能比职业性哮喘更为常见 2 到 3 倍。高分子量蛋白和低分子量化学物质都可能引起职业性鼻炎。诊断基于职业史,如果合适,还需要记录对致病物的 IgE 介导的致敏情况。职业性鼻炎的管理与非职业性鼻炎相似,包括消除或减少接触致病物,同时进行药物治疗。如果治疗变应原可获得,并且合适的话,也可以考虑变应原免疫治疗。