Harvey Richard J, Winder Mark, Parmar Priscilla, Lund Valerie
Department of Otolaryngology/Skull Base Surgery, St Vincent's Hospital, Victoria Street, Darlinghurst, Sydney, New South Wales 2010, Australia.
Otolaryngol Clin North Am. 2011 Oct;44(5):1081-140. doi: 10.1016/j.otc.2011.06.020.
Management of malignant neoplasms of the sinonasal tract and skull base is hampered by the relative low incidence and pathologic diversity of patient presentations. Many studies have reported successful outcomes in the endoscopic management of malignancy since 1996, and these are summarized in this article. Nonsurgical adjuvant therapies are important for locoregional control because surgery occurs in a restricted anatomic space with close margins to critical structures, and distant disease is an ongoing concern in these disorders. There remains a need for collaborative consistent multicenter reporting, and international registries have been established to assist in such efforts.
鼻窦和颅底恶性肿瘤的治疗因患者表现的相对低发病率和病理多样性而受到阻碍。自1996年以来，许多研究报告了内镜治疗恶性肿瘤的成功结果，本文对此进行了总结。非手术辅助治疗对于局部区域控制很重要，因为手术发生在解剖空间受限且与关键结构边缘接近的区域，并且远处转移在这些疾病中一直是一个令人担忧的问题。仍然需要进行协作一致的多中心报告，并且已经建立了国际登记处来协助开展此类工作。
