1. Department of Pathology, The Third Affiliated Hospital, Guangzhou Medical University, Guangzhou, 510150, China.
J Cancer. 2011;2:484-9. doi: 10.7150/jca.2.484. Epub 2011 Sep 30.
We report a case of a metastatic signet ring cell carcinoma (SRCC) of gastrointestinal tract. The case is very rare because gastrointestinal tract SRCC was metastatic to bilateral breasts and ovaries (Krukenberg tumor) in the same young woman almost synchronously under breastfeeding condition. Though the primary site was not detected, IHC results fully verified that the tumor originated from gastrointestinal tract. The severe situation of the patient was believed to be connected to her high estrogen hormone.
我们报告了一例胃肠道转移性印戒细胞癌(SRCC)病例。这种情况非常罕见,因为在哺乳期间,同一年轻女性的胃肠道 SRCC 几乎同时转移到双侧乳房和卵巢(克鲁肯伯格肿瘤)。尽管未发现原发灶,但免疫组化结果充分证实肿瘤来源于胃肠道。患者的严重病情被认为与她体内高雌激素水平有关。