Department of Pediatrics, Tokyo Medical University.
Asian Pac J Allergy Immunol. 2011 Jun;29(2):150-60.
To review baboon syndrome (BS).
Date sources were obtained from PubMed and Google Scholar: Photographs of baboon syndrome were obtained from our patient.
PubMed and Google Scholar were searched up to June 30, 2010. The search terms were "baboon syndrome", "SDRIFE" and "thimerosal allergy". Reverse references from relevant articles and Google Scholar were also used. As BS is a classical disease and cases of offending agents were relatively old, some references were more than five years old. In order to gather as many cases of offending agents as possible, more than 50 references were collected.
We divided BS into as 4 groups; classical baboon syndrome, topical drug-induced baboon syndrome, systemic drug-induced baboon syndrome and symmetrical drug-related intertriginous and flexural exanthema (SDRIFE). The pathomechanism of BS is still unknown. A delayed type of hypersensitivity reaction, a recall phenomenon, pharmacologic interaction with immune-receptors and anatomical factors may be involved in the causation of BS.
综述狒狒综合征（BS）。
资料来源于 PubMed 和 Google Scholar：BS 的照片来自我们的患者。
检索词为“狒狒综合征”“SDRIFE”和“硫柳汞过敏”，检索时间截至 2010 年 6 月 30 日，检索了 PubMed 和 Google Scholar。还查阅了相关文章的反向参考文献和 Google Scholar。由于 BS 是一种经典疾病，且致病药物相对较老，因此一些参考文献的时间超过了 5 年。为了尽可能多地收集致病药物，收集了 50 多篇参考文献。
将 BS 分为 4 组：经典狒狒综合征、局部药物诱导的狒狒综合征、全身药物诱导的狒狒综合征和对称性药物相关的间擦疹和褶皱疹（SDRIFE）。BS 的发病机制尚不清楚。迟发型超敏反应、回忆现象、与免疫受体的药物相互作用和解剖因素可能与 BS 的发病有关。
