Uluğ Mehmet, Yaman Yöntem, Yapici Ferda, Can-Uluğ Nuray
Department of Infectious Diseases and Clinic Microbiology, Ozel Umit Hospital, Eskişehir, Turkey.
Turk J Pediatr. 2011 Jul-Aug;53(4):413-24.
Brucellosis, whether in an endemic region or not, remains a diagnostic puzzle due to occasional misleading unusual presentations and non-specific symptoms. The aim of this study was to evaluate the clinical and laboratory findings, complications and treatment outcome of brucellosis in children in southeastern Anatolia, Turkey. This study focuses on the frequency of clinical and laboratory findings and complications in cases with brucellosis. Of 22 patients, 8 (36.3%) were female and 14 (63.7%) were male. Fever, malaise, lack of appetite, arthralgia, and night sweating were the main presenting symptoms overall. Hematologic complications (n=13, 59.1%) were most common, followed by skeletal (n=7, 31.8%) and cutaneous system (n=1, 4.5%). Brucellosis may affect any organ system and imitate a variety of clinical entities. Diagnosis of brucellosis should be considered whenever there is a febrile illness associated with rheumatological complaints. Consequently, early recognition of the infection, prolonged antibiotic treatment and careful long-term follow-up should improve the patient outcome.
布鲁氏菌病，无论是否处于流行地区，由于偶尔出现误导性的异常表现和非特异性症状，仍然是一个诊断难题。本研究的目的是评估土耳其安纳托利亚东南部儿童布鲁氏菌病的临床和实验室检查结果、并发症及治疗效果。本研究关注布鲁氏菌病病例的临床和实验室检查结果及并发症的发生频率。22例患者中，8例（36.3%）为女性，14例（63.7%）为男性。发热、乏力、食欲不振、关节痛和盗汗是总体上的主要症状表现。血液学并发症（n = 13，59.1%）最为常见，其次是骨骼系统并发症（n = 7，31.8%）和皮肤系统并发症（n = 1，4.5%）。布鲁氏菌病可累及任何器官系统，并可模仿多种临床病症。每当出现伴有风湿性症状的发热性疾病时，都应考虑布鲁氏菌病的诊断。因此，早期识别感染、延长抗生素治疗时间以及仔细的长期随访应可改善患者的预后。
