Department of Nephrology, Sydney Children's Hospital, Randwick, NSW, Australia.
Acta Paediatr. 2012 Mar;101(3):224-9. doi: 10.1111/j.1651-2227.2011.02482.x. Epub 2011 Oct 29.
Voiding cystourethrography (VCUG) is commonly performed to screen for vesicoureteric reflux or other urological anomalies but has a potential to provoke distress in infants and children. We performed a systematic review of randomized controlled trials of interventions to reduce distress, pain or anxiety during VCUG. Eight trials (591 participants) met the inclusion criteria.
Conscious sedation with midazolam effectively alleviates the distress of VCUG in children older than 1 year of age. Psychological preparation and warmed contrast medium may also be effective. Nitrous oxide 50% may be an alternative to midazolam, but further evidence is needed.
排尿性膀胱尿道造影术(VCUG)常用于筛查膀胱输尿管反流或其他泌尿道异常,但可能会引起婴儿和儿童的不适。我们对旨在减轻 VCUG 期间不适、疼痛或焦虑的干预措施的随机对照试验进行了系统评价。有 8 项试验(591 名参与者)符合纳入标准。
咪达唑仑镇静可有效缓解 1 岁以上儿童 VCUG 的不适。心理准备和温热的对比剂也可能有效。50%氧化亚氮可能是咪达唑仑的替代药物,但需要更多证据。