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单侧性痣样毛细血管扩张伴神经系统病变。

Unilateral nevoid telangiectasia accompanied by neurological disorders.

机构信息

Department of Dermatology and Venerology, Akdeniz University, School of Medicine Antalya, Turkey.

出版信息

J Eur Acad Dermatol Venereol. 2011 Nov;25(11):1356-9. doi: 10.1111/j.1468-3083.2010.03967.x. Epub 2011 Jan 17.

DOI:10.1111/j.1468-3083.2010.03967.x
PMID:21981341
Abstract

BACKGROUND

Unilateral nevoid telangiectasia (UNT) is a unique vascular dermatosis of ambiguous aetiology.

OBJECTIVE

To investigate the role of neurological disorder in pathogenesis of the UNT.

METHODS

We investigated eight consecutive patients with unilateral nevoid telangiectasia. Detailed dermatological and neurological examinations, and magnetic resonance imaging were performed on each patient. In case of presence of dysesthesia over the skin lesion, electroneuromyography was performed to determine any relationships between lesions and peripheral neuropathy.

RESULTS

All the patients had hypoesthesia over the skin lesion. The cranial magnetic resonance imaging showed subcortical hamartomatous lesions in one patient and demyelinized plaques on the corpus of the caudate nucleus and the pontin area in another. Electroneuromyography evaluation was nonspecific.

CONCLUSION

In our study, neurological disorders were associated with UNT. Thus, it can be speculated that neurological disorders might contribute to the development and/or progression of UNT. Patients with UNT should be encouraged for neurological investigation.

摘要

背景

单侧痣样毛细血管扩张症(UNT)是一种病因不明的独特血管性皮肤病。

目的

探讨神经系统疾病在 UNT 发病机制中的作用。

方法

我们对 8 例单侧痣样毛细血管扩张症患者进行了研究。对每位患者进行详细的皮肤科和神经系统检查及磁共振成像。如果皮肤病变伴有感觉异常,进行肌电图检查以确定病变与周围神经病变之间的关系。

结果

所有患者皮肤病变处均有感觉减退。1 例头颅磁共振成像显示皮质下错构瘤样病变,另 1 例尾状核体部和脑桥区脱髓鞘斑块。肌电图评估无特异性。

结论

在我们的研究中,神经系统疾病与 UNT 相关。因此,可以推测神经系统疾病可能有助于 UNT 的发展和/或进展。应鼓励 UNT 患者进行神经系统检查。

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