Abal-Díaz L, Soria X, Casanova-Seuma J M
Servicio de Dermatología, Hospital Universitari Arnau de Vilanova, Lleida, Spain.
Actas Dermosifiliogr. 2012 Jun;103(5):376-87. doi: 10.1016/j.ad.2011.07.002. Epub 2011 Oct 7.
Scarring alopecia refers to a group of disorders of various etiologies that cause permanent hair loss. In this article, we focus on primary cicatricial alopecia, a group of diseases in which the hair follicle is the main target of the inflammatory process. These disorders are currently classified as lymphocytic, neutrophilic, or mixed according to the cells that make up the inflammatory infiltrate. The pathogenesis of the majority of these conditions is not fully understood and they may have similar clinical features, often making it necessary to perform 1 or more skin biopsies in order to reach a diagnosis. Management depends on early and accurate diagnosis and aggressive treatment in some cases in order to prevent follicular destruction and scarring.
瘢痕性脱发是指由各种病因引起的一组导致永久性脱发的疾病。在本文中，我们重点关注原发性瘢痕性脱发，这是一组以毛囊为炎症过程主要靶点的疾病。根据构成炎症浸润的细胞，这些疾病目前分为淋巴细胞性、中性粒细胞性或混合性。这些疾病中的大多数发病机制尚未完全明确，它们可能具有相似的临床特征，因此通常需要进行一次或多次皮肤活检才能做出诊断。治疗取决于早期准确的诊断，在某些情况下还需要积极治疗，以防止毛囊破坏和瘢痕形成。
