Department of Analytical Chemistry, Campus of Rabanales, University of Córdoba, Córdoba, Spain.
J Chromatogr A. 2011 Nov 18;1218(46):8295-302. doi: 10.1016/j.chroma.2011.09.048. Epub 2011 Sep 22.
Haloacetaldehydes (HAs) are becoming the most widespread disinfection by-products (DBPs) found in drinking water, besides trihalomethanes and haloacetic acids, generated by the interaction of chemical disinfectants with organic matter naturally present in water. Because of their high potential toxicity, HAs have currently received a singular attention, especially trichloroacetaldehyde (chloral hydrate, CH), the most common and abundant compound found in treated water. The aims of this study are focused on the miniaturisation of EPA Method 551.1, including some innovations such as the use of ethyl acetate as the extracting solvent, the enhancement of HAs stability in aqueous solutions by adjusting the pH ~3.2 and the use of a large-volume sample injection (30 μL) coupled to programmed temperature vaporizer-gas chromatography-mass spectrometry to improve both sensitivity and selectivity. In optimised experimental conditions, the limits of detection for the 7 HAs studied ranged from 6 to 20 ng/L. Swimming pools have recently been recognized as an important source of exposure to DBPs and as a result, in this research for the first time, HAs have been determined in this type of water. Two HAs have been found in the analysed water: CH at concentrations between 1.2-38 and 53-340 μg/L and dichloroacetaldehyde between 0.07-4.0 and 1.8-23 μg/L in tap and swimming pool waters, respectively.
卤代乙二醛（HAs）是继三卤甲烷和卤乙酸之后在饮用水中发现的分布最广泛的消毒副产物（DBPs），它们是由化学消毒剂与水中天然存在的有机物相互作用产生的。由于其潜在的高毒性，HAs 目前受到了特别关注，特别是三氯乙醛（水合氯醛，CH），这是在处理水中最常见和最丰富的化合物。本研究的目的是对 EPA 方法 551.1 进行微型化，包括一些创新，如使用乙酸乙酯作为提取溶剂、通过调节 pH~3.2 来增强水溶液中 HAs 的稳定性，以及使用大体积（30 μL）进样与程序升温汽化-气相色谱-质谱联用，以提高灵敏度和选择性。在优化的实验条件下，7 种研究 HAs 的检出限范围为 6 至 20 ng/L。最近，游泳池被认为是 DBPs 暴露的一个重要来源，因此，在这项研究中，HAs 首次在这种水中被检测到。在所分析的水中发现了两种 HAs：CH 的浓度在 1.2-38 和 53-340 μg/L 之间，而二氯乙醛的浓度在 0.07-4.0 和 1.8-23 μg/L 之间，分别存在于自来水和游泳池水中。
