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[治疗性细胞血管生成在周围动脉疾病治疗中的应用]

[Therapeutic cellular angiogenesis in treatment of peripheral artery diseases].

作者信息

Khorev N G, Elykomov V A, Zaloznyĭ D A

出版信息

Angiol Sosud Khir. 2011;17(2):36-44.

PMID:21983460
Abstract

High incidence of peripheral artery disease and limited possibilities of either open or endovascular methods of treatment, as well as low efficacy of medicamentous treatment of this pathology compel the professionals concerned to search for new methods of treatment aimed at improving the condition of the distal arterial bed, decreasing peripheral resistance and stimulating the development of the capillary network. One of the possible ways to solve this problem is the use of cellular technologies for stimulating angiogenesis. This novel and rather promising method consists in using autologous cell therapy in treatment of peripheral arterial diseases.

摘要

外周动脉疾病的高发病率以及开放或血管内治疗方法的有限可能性,加之该病症药物治疗效果不佳,促使相关专业人员寻找旨在改善远端动脉床状况、降低外周阻力并刺激毛细血管网络发育的新治疗方法。解决这一问题的一种可能途径是利用细胞技术刺激血管生成。这种新颖且颇具前景的方法在于使用自体细胞疗法治疗外周动脉疾病。

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