Department of Biochemistry, PMAS-Arid Agriculture University, Rawalpindi, Pakistan.
Res Vet Sci. 2012 Oct;93(2):795-7. doi: 10.1016/j.rvsc.2011.09.013. Epub 2011 Oct 7.
The present study was planned to evaluate the possible transmission of ochratoxin A (OTA) in serum and targeted organs of broilers fed on two levels (500 and 1000 ppb) this toxin in the presence or absence of a toxin deactivator (containing a mycotoxin deactivating yeast Trichosporon mycotoxinivorans) at two inclusion levels (1 and 2 kg/ton of feed) to 270 day-old broiler chicks divided into nine groups (A-I) over a 42 days period. Serum samples were collected at 14, 28 and 42nd day of experiment, whereas, liver and kidney tissues were obtained from broilers slaughtered at 42nd day of experiment. The highest OTA levels were detected in serum, livers and kidneys of OTA treated groups without supplementation of toxin deactivator (groups D and G) at day 42 of experiment, while the residues were significantly (P<0.01) lower in treatment groups (F and I) supplemented with toxin deactivator at 2 kg/ton of feed. The order of OTA level was serum>kidneys>liver.
本研究旨在评估在 270 日龄肉鸡中以两种水平(500 和 1000 ppb)摄入赭曲霉毒素 A(OTA)并添加或不添加(含有霉菌毒素去活酵母 Trichosporon mycotoxinivorans)两种添加水平(1 和 2 千克/吨饲料)条件下,OTA 在血清和靶器官中的可能传递。血清样本分别在实验的第 14、28 和 42 天采集,而在实验的第 42 天屠宰肉鸡后采集肝脏和肾脏组织。在未添加毒素去活剂的 OTA 处理组(D 和 G 组)中,血清、肝脏和肾脏中的 OTA 含量在实验的第 42 天最高,而在添加毒素去活剂 2 千克/吨饲料的处理组(F 和 I 组)中,残留量显著(P<0.01)较低。OTA 水平的顺序为血清>肾脏>肝脏。