Institute of Chemical Biology and Fundamental Medicine, SB RAS, 630090 Novosibirsk, Russian Federation.
Infect Genet Evol. 2011 Dec;11(8):1842-61. doi: 10.1016/j.meegid.2011.09.019. Epub 2011 Oct 1.
The family Anaplasmataceae includes gram-negative obligate intracellular alphaproteobacteria, which amplify within membrane-bound vacuoles. The genera Anaplasma and Ehrlichia as well as the recently specified cluster "Candidatus Neoehrlichia" comprise all bacteria of the family that are transmitted by ixodid ticks to mammalian hosts and cause infections in humans and numerous domestic and wild animal species. Totally, six Anaplasma, five Ehrlichia, and two "Candidatus Neoehrlichia" species as well as a variety of Ehrlichia bacteria with undefined taxonomic position belong to tick-borne bacteria. This review briefs the ecology, pathogenic properties, and molecular genetic diversity of Anaplasmataceae validated species, "Candidatus" species, and undefined novel Ehrlichia genetic variants.
该家族包括革兰氏阴性专性细胞内α变形菌，在膜结合的空泡内扩增。属种包括立克次体和埃立克体以及最近指定的“候选新埃立克体”群，构成了所有通过硬蜱传播给哺乳动物宿主并在人类和众多家养和野生动物物种中引起感染的家族细菌。总共，有六种立克次体、五种埃立克体和两种“候选新埃立克体”以及多种具有未定义分类地位的埃立克体细菌属于蜱传细菌。本综述简要介绍了已验证的种、“候选”种和未定义的新型埃立克体遗传变体的生态学、致病性和分子遗传多样性。
