The efficacy of miRNA122, a novel therapeutic target, for predicting the progression of hepatocellular carcinoma (HCC).
作者信息
Wang Lifeng, Zhang Zheng, Wang Fu-Sheng
机构信息
Research Center for Biological Therapy, The Institute of Translational Hepatology, Beijing 302 Hospital, Beijing, China.
出版信息
Cell Mol Immunol. 2012 Mar;9(2):103-4. doi: 10.1038/cmi.2011.43. Epub 2011 Oct 10.
Abstract
摘要
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MicroRNA-22 and microRNA-140 suppress NF-κB activity by regulating the expression of NF-κB coactivators.MicroRNA-22 和 microRNA-140 通过调节 NF-κB 共激活因子的表达来抑制 NF-κB 活性。
Biochem Biophys Res Commun. 2011 Aug 12;411(4):826-31. doi: 10.1016/j.bbrc.2011.07.048. Epub 2011 Jul 21.
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MicroRNA122 is a key regulator of α-fetoprotein expression and influences the aggressiveness of hepatocellular carcinoma.微小 RNA122 是甲胎蛋白表达的关键调节因子，影响肝癌的侵袭性。
Nat Commun. 2011 Jun 7;2:338. doi: 10.1038/ncomms1345.
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MicroRNA profiling in cancer.癌症中的 microRNA 分析。
Clin Sci (Lond). 2011 Aug;121(4):141-58. doi: 10.1042/CS20110005.
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The role of microRNAs in liver cancer progression.微小 RNA 在肝癌进展中的作用。
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AFP, AFP-L3, DCP, and GP73 as markers for monitoring treatment response and recurrence and as surrogate markers of clinicopathological variables of HCC.甲胎蛋白、甲胎蛋白异质体 3、脱γ-羧基凝血酶原和高尔基糖蛋白 73 作为监测治疗反应和复发的标志物，以及 HCC 临床病理变量的替代标志物。
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J Biol Chem. 2009 Nov 13;284(46):32015-27. doi: 10.1074/jbc.M109.016774. Epub 2009 Sep 2.
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