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Confirmation of R132H mutation of isocitrate dehydrogenase 1 as an independent prognostic factor in anaplastic astrocytoma.

作者信息

Schittenhelm Jens, Mittelbronn Michel, Meyermann Richard, Melms Arthur, Tatagiba Marcos, Capper David

出版信息

Acta Neuropathol. 2011 Nov;122(5):651-2. doi: 10.1007/s00401-011-0885-0. Epub 2011 Oct 8.

DOI:10.1007/s00401-011-0885-0
PMID:21983902
Abstract
摘要

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H3 K27M 突变在成人中线胶质瘤中的高频发生。
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J Neurooncol. 2017 Jan;131(1):93-101. doi: 10.1007/s11060-016-2272-0. Epub 2016 Sep 7.
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ATRX immunostaining predicts IDH and H3F3A status in gliomas.ATRX 免疫组化可预测胶质瘤的 IDH 和 H3F3A 状态。
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Prognostic role of IDH mutations in gliomas: a meta-analysis of 55 observational studies.异柠檬酸脱氢酶(IDH)突变在胶质瘤中的预后作用:55项观察性研究的荟萃分析
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Analysis of IDH1-R132 mutation, BRAF V600 mutation and KIAA1549-BRAF fusion transcript status in central nervous system tumors supports pediatric tumor classification.对中枢神经系统肿瘤中异柠檬酸脱氢酶1(IDH1)-R132突变、BRAF V600突变及KIAA1549-BRAF融合转录本状态的分析有助于小儿肿瘤的分类。
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