Department of Psychiatry, Royal College of Surgeons in Ireland, RCSI Education and Research Centre, Beaumont Hospital, Dublin 9, Ireland.
Br J Psychiatry. 2011 Dec;199(6):508-9. doi: 10.1192/bjp.bp.111.092197. Epub 2011 Oct 7.
We present four cases of confirmed anti-NMDA receptor encephalitis; three presented initially with serious psychiatric symptoms and the other developed significant psychiatric symptoms during the initial phase of illness. Brain biopsy findings of one patient are also described. Psychiatrists should consider anti-NMDA receptor encephalitis in patients presenting with psychosis and additional features of dyskinesias, seizures and catatonia, particularly where there is no previous history of psychiatric disorder.
我们报告了 4 例确诊的抗 N- 甲基-D- 天冬氨酸受体脑炎病例;其中 3 例最初表现为严重的精神症状,另 1 例在疾病初始阶段出现明显的精神症状。还描述了 1 例患者的脑组织活检结果。当精神科医生遇到以精神病为主要表现且伴有运动障碍、癫痫发作和紧张症等其他特征的患者时,特别是在没有既往精神障碍病史的情况下,应考虑抗 N- 甲基-D- 天冬氨酸受体脑炎。