Morino M, Alabiso O, Sandrucci S
Istituto di Clinica Chirurgica Generale e Terapia Chirurgica, Università degli Studi di Torino.
Minerva Chir. 1990 Mar 15;45(5):207-14.
On the basis of six surgically operated patients, current thinking with regard to the treatment of Zollinger-Ellison syndrome is outlined. Total gastrectomy which for many years was the most common surgical intervention, is now confined to just a very specially indicated few cases because the introduction of anti-H2 gives good control of gastric secretion. The operation should therefore be targeted at removing the gastrinoma, helped in this by modern methodologies for pinpointing the neoplasia. Long-term however include a certain number of failures.
基于六例接受手术治疗的患者，概述了目前关于卓艾综合征治疗的思路。全胃切除术多年来一直是最常见的手术干预方式，如今仅适用于极少数有特殊指征的病例，因为抗H2药物的应用能很好地控制胃酸分泌。因此，手术应旨在切除胃泌素瘤，现代定位肿瘤的方法有助于实现这一目标。然而，长期来看仍有一定数量的治疗失败病例。
