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大量血液回收计划中回输的红细胞体积:都去哪儿了?

The volume of returned red blood cells in a large blood salvage program: where does it all go?

机构信息

Department of Anesthesiology, Magee Womens Hospital, Pittsburgh, Pennsylvania 15213, USA.

出版信息

Transfusion. 2011 Oct;51(10):2126-32. doi: 10.1111/j.1537-2995.2011.03111.x. Epub 2011 Mar 24.

Abstract

BACKGROUND

Intraoperative blood salvage is the process whereby shed red blood cells (RBCs) are collected and returned to the patient. We analyzed the trends in the volume of returned RBCs by our blood salvage program across a 12-hospital regional health care system over a 5-year period.

STUDY DESIGN AND METHODS

All quality control, RBC recovery, and patient demographic data relating to blood salvage are stored in a large database covering these 12 hospitals. Cases in which blood salvage was performed over a 5-year period were stratified based on patient demographics, hospital, type of surgery, and volume of RBCs recovered.

RESULTS

There were 19,867 surgeries performed during the study period in which blood salvage was used. The median volume of blood returned to each patient was 405 mL (25th-75th percentile, 135-750 mL). Defining the volume of an RBC unit as 200 mL, this represented a median of 1.1 RBC unit equivalents (25th-75th percentile, 0.37-2.1 units) returned to each patient. For the majority of patients, not more than 1 RBC unit equivalent was recovered. Overall, the ratio of cases where at least 1 RBC unit equivalent was recovered to cases where less than 1 RBC equivalent was recovered was 2.5:1; this ratio varied considerably between surgical procedures.

CONCLUSIONS

Although overall the mean volumes of RBCs returned to the patients by intraoperative blood salvage were high, the actual volumes returned depended on the case mix. There appears to be an opportunity to use blood salvage more selectively to improve efficiency.

摘要

背景

术中血液回收是指收集并将流失的红细胞(RBC)回输给患者的过程。我们分析了在一个由 12 家医院组成的区域性医疗系统中,5 年内通过血液回收计划回收的 RBC 量的趋势。

研究设计与方法

所有与血液回收相关的质量控制、RBC 回收和患者人口统计学数据均存储在一个大型数据库中,涵盖了这 12 家医院。根据患者人口统计学、医院、手术类型和回收的 RBC 量,对 5 年内进行血液回收的病例进行分层。

结果

在研究期间,共进行了 19867 例手术,其中使用了血液回收。每位患者回输的 RBC 中位数为 405 毫升(25-75 百分位数,135-750 毫升)。将一个 RBC 单位定义为 200 毫升,这代表每位患者回输的 RBC 单位当量中位数为 1.1(25-75 百分位数,0.37-2.1 单位)。对于大多数患者,回输的 RBC 单位当量不超过 1。总体而言,至少回收 1 个 RBC 单位当量的病例与回收不到 1 个 RBC 单位当量的病例比例为 2.5:1;这一比例在不同手术程序之间差异很大。

结论

尽管术中血液回收回输给患者的 RBC 平均体积较高,但实际回输量取决于病例组合。似乎有机会更有选择性地使用血液回收来提高效率。

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