光动力疗法治疗儿童Best病合并脉络膜新生血管化
Photodynamic therapy for best disease complicated by choroidal neovascularization in children.
作者信息
Ozdek Sengul, Ozmen Mehmet Cuneyt, Tufan Hasan Ali, Gurelik Gokhan, Hasanreisoglu Berati
机构信息
Gazi University, School of Medicine, Ophthalmology Department, Ankara, Turkey.
出版信息
J Pediatr Ophthalmol Strabismus. 2012 Jul-Aug;49(4):216-21. doi: 10.3928/01913913-20111004-01. Epub 2011 Oct 11.
PURPOSE
To describe the results of photodynamic therapy (PDT) with verteporfin for the treatment of choroidal neovascularization (CNV) associated with Best vitelliform macular dystrophy (BVMD) in children.
METHODS
Five eyes of four children diagnosed as having BVMD complicated by CNV received a single session of PDT. Response to treatment was monitored with fluorescein angiography and optical coherence tomography.
RESULTS
All eyes responded well to one session of PDT with significant increases in visual acuity in four of the five eyes. Increase or stabilization of visual acuity was preserved during a mean follow-up period of 25 months.
CONCLUSION
PDT may be an effective treatment for CNV associated with BVMD in children.
目的
描述用维替泊芬进行光动力疗法（PDT）治疗儿童Best卵黄样黄斑营养不良（BVMD）相关脉络膜新生血管（CNV）的结果。
方法
4名诊断为BVMD合并CNV的儿童的5只眼接受了单次PDT治疗。通过荧光素血管造影和光学相干断层扫描监测治疗反应。
结果
所有眼睛对单次PDT反应良好，5只眼中有4只眼视力显著提高。在平均25个月的随访期内，视力保持提高或稳定。
结论
PDT可能是治疗儿童BVMD相关CNV的有效方法。
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