Beijing Anding Hospital, Capital Medical University, Beijing, China.
J Psychiatr Ment Health Nurs. 2011 Nov;18(9):751-7. doi: 10.1111/j.1365-2850.2010.01677.x. Epub 2011 Sep 14.
This study aimed to assess insight in Chinese schizophrenia patients and to identify its relationship with socio-demographic and clinical factors, executive functions and quality of life (QOL). A cohort of 139 clinically stable schizophrenia patients was selected by consecutively screening patients diagnosed with schizophrenia who were attending the outpatient department of a university-affiliated psychiatric hospital in China. Participants' socio-demographic and clinical characteristics, including psychotic symptoms, depression and insight, as well as QOL and executive functions, were periodically assessed with standardized rating instruments. Patients received standard psychiatric care and were followed up for 1 year. Impaired insight was found to be common in stable Chinese schizophrenia patients (76.3%), with merely 5% showing improvement over the 1-year follow-up. Insight was inversely correlated with positive and negative symptoms at all but the 12-month assessment and with both the physical and mental components of QOL at baseline and the 12-month assessment. Insight was not associated with depressive symptoms or executive functions. Standard psychiatric care does not improve the level of insight in clinically stable Chinese schizophrenia outpatients, which warrants the introduction of specific therapeutic interventions that enhance insight.
本研究旨在评估中国精神分裂症患者的自知力,并确定其与社会人口学和临床因素、执行功能和生活质量(QOL)的关系。通过连续筛查在中国某大学附属医院精神科门诊就诊的精神分裂症患者,选择了 139 名临床稳定的精神分裂症患者作为队列。定期使用标准化评定工具评估参与者的社会人口学和临床特征,包括精神病症状、抑郁和自知力,以及生活质量和执行功能。患者接受标准的精神科护理,并随访 1 年。研究发现,稳定的中国精神分裂症患者自知力受损较为常见(76.3%),仅有 5%的患者在 1 年随访中有所改善。自知力与阳性和阴性症状在所有评估中均呈负相关,但在 12 个月评估中除外,与基线和 12 个月评估时的躯体和心理生活质量组成部分均呈负相关。自知力与抑郁症状或执行功能无关。标准的精神科护理并不能提高临床稳定的中国精神分裂症门诊患者的自知力水平,因此需要引入增强自知力的特定治疗干预措施。