Ojha Sandeep S, Naik Leena P, Fernandes Gwendolyn C, Sathe Pragati A, Kandalkar Bhuvaneshwari M
Department of Cytopathology, King Edward Memorial Hospital, Mumbai, India.
Acta Cytol. 2011;55(5):481-4. doi: 10.1159/000330679. Epub 2011 Oct 8.
Infantile digital fibromatosis (IDF) or inclusion body fibromatosis is a benign proliferation of fibroblastic and myofibroblastic cells. Its most common site is the digits of young children and it is named for the intracytoplasmic inclusions that are detected in lesional cells.
A two and a half-year-old male child presented with a single flesh-colored nodule on the dorsal aspect of his right little toe since the sixth month of life. FNAC from the lesion showed characteristic cytomorphological features of IDF.
IDF is a rare lesion occurring in children or infants. There are many case reports describing histopathological features of IDF. To our knowledge, the typical inclusion bodies as cytomorphological findings in IDF have not been described in the literature. This is a rare case diagnosed on cytology and confirmed on histopathology.
婴儿指纤维瘤病(IDF)或包涵体纤维瘤病是成纤维细胞和肌成纤维细胞的良性增殖。其最常见部位是幼儿的手指,因其在病变细胞中检测到的胞质内包涵体而得名。
一名两岁半男童自出生六个月起,右小趾背侧出现一个肉色结节。病变部位的细针穿刺抽吸活检(FNAC)显示出IDF的特征性细胞形态学特征。
IDF是一种发生于儿童或婴儿的罕见病变。有许多病例报告描述了IDF的组织病理学特征。据我们所知,IDF中作为细胞形态学表现的典型包涵体在文献中尚未被描述。这是一例经细胞学诊断并经组织病理学证实的罕见病例。