Kawaguchi M, Mitsuhashi Y, Hozumi Y, Kondo S
Department of Dermatology, Yamagata University School of Medicine, Japan.
J Dermatol. 1998 Aug;25(8):523-6. doi: 10.1111/j.1346-8138.1998.tb02448.x.
We reported a fourteen-month-old boy with infantile digital fibromatosis. At the age of seven months, a nodule appeared on the back of the left third toe, and developed into a slight red tumor divided into five hemispherical nodules. Histopathologically, spindle-shaped tumor cells with an eosinophilic inclusion body in the cytoplasm were seen in the dermis. Electron microscopy showed a dense body in the cytoplasm of the tumor cells. One year and two months after the first visit, the tumor regressed without any aggressive treatment. Japanese cases of infantile digital fibromatosis were reviewed. The literature review and our case suggest that the tumor should be observed without any aggressive treatment unless it causes mobile dysfunction of the affected finger or toe.
我们报告了一名患有婴儿指纤维瘤病的14个月大男孩。7个月大时，左足第三趾背侧出现一个结节，随后发展为一个微红的肿瘤，分为5个半球形结节。组织病理学检查显示，真皮内可见梭形肿瘤细胞，其细胞质中有嗜酸性包涵体。电子显微镜检查显示肿瘤细胞的细胞质中有一个致密体。首次就诊后1年零2个月，肿瘤未经任何积极治疗即自行消退。我们回顾了日本的婴儿指纤维瘤病病例。文献回顾及我们的病例提示，除非该肿瘤导致患指或患趾活动功能障碍，否则应进行观察，无需任何积极治疗。
