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手术在小细胞肺癌中的作用。

Role of surgery in small cell lung cancer.

作者信息

Goldstein Seth D, Yang Stephen C

机构信息

General Surgery, Johns Hopkins University School of Medicine, 600 North Wolfe Street, Blalock 240, Baltimore, MD 21287, USA.

出版信息

Surg Oncol Clin N Am. 2011 Oct;20(4):769-77. doi: 10.1016/j.soc.2011.08.001.

Abstract

Conventional treatment for small cell lung cancer (SCLC) is currently thoracic radiation and combination chemotherapy, and surgery has been traditionally stated to have little to no role in disease management. However, a growing body of literature suggests that early-stage SCLC may be more amenable to local control following resection, with surgery being an important component of multimodality therapy. This article attempts to summarize what is currently known about early-stage SCLC, and outlines the methods by which this controversy is actively being investigated.

摘要

小细胞肺癌(SCLC)的传统治疗方法目前是胸部放疗和联合化疗,传统观点认为手术在疾病管理中作用很小或几乎没有作用。然而,越来越多的文献表明,早期小细胞肺癌在切除术后可能更易于局部控制,手术是多模式治疗的重要组成部分。本文试图总结目前关于早期小细胞肺癌的已知情况,并概述正在积极研究这一争议的方法。

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