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临床评估脱矿骨同种异体移植物在人类窦提升中的应用:一项临床和组织学研究。

Clinical evaluation of demineralized bone allograft for sinus lifts in humans: a clinical and histologic study.

机构信息

Department of Oral & Maxillofacial Surgery, School of Dentistry, Chosun University, Gwangju, Republic of Korea.

出版信息

Implant Dent. 2011 Dec;20(6):460-4. doi: 10.1097/ID.0b013e31823541e7.

Abstract

PURPOSE

Severe alveolar bony resorption in the edentulous posterior maxilla and pneumatization of the maxillary sinus wall make traditional implant placement impossible in the posterior maxilla. To reconstruct the severely resorbed maxilla for dental implant placement, 1 successful technique is to elevate the maxillary sinus floor using demineralized bone matrix (DBM) grafts. The purpose of this study was to evaluate a histologic and histomorphometric evaluation of DBM grafts in the human maxilla.

PATIENTS AND METHODS

Nine months after grafting, at the time of dental implantation, biopsy samples were taken from the grafted areas of 8 patients and were analyzed histologically.

RESULTS

All the sinus lifts were successful in the clinical study conducted after implantation. Resorption of the graft materials and new bone formation were observed, and there was direct deposition of bone on the surface of the graft particles.

CONCLUSION

The results of this study indicate that limited maxillary sinus lift with DBM graft material is a clinically reliable preimplant procedure.

摘要

目的

无牙后牙槽嵴严重吸收和上颌窦气化使传统的种植体在后上颌无法放置。为了重建严重吸收的上颌骨以进行牙种植体放置,一种成功的技术是使用脱矿骨基质 (DBM) 移植物抬高上颌窦底。本研究的目的是评估 DBM 移植物在人上颌骨中的组织学和组织形态计量学评价。

患者和方法

在种植后的 9 个月,即种植时,从 8 名患者的移植物区域采集活检样本进行组织学分析。

结果

在植入后的临床研究中,所有窦提升均成功。观察到移植物材料的吸收和新骨形成,并且在移植物颗粒表面有直接的骨沉积。

结论

本研究结果表明,使用 DBM 移植物进行有限的上颌窦提升是一种临床可靠的种植前程序。

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