Cacciafesta M, Marigliano V, Piccirillo G, Brioli D, Scuteri A, Campana F, Ferretti F
Istituto di I Clinica medica, Università La Sapienza, Roma.
Recenti Prog Med. 1990 May;81(5):344-50.
NMR is still considered essentially, in the field of ischemic brain vascular disease, an imaging method. On the contrary, Authors review MR-spectroscopy possibilities, emphasizing that by this method it is possible to achieve a complete and dynamic study of brain energy metabolism, and therefore to identify markers of cellular injury clearly more sensitive and precocious than MRI morphological findings. Moreover, this method allows to easily evaluate cerebral blood flow, pharmacologic treatment efficacy, effects of eventual metabolic abnormalities on ischemia's evolution.
在缺血性脑血管疾病领域,核磁共振成像(NMR)本质上仍被视为一种成像方法。相反,作者回顾了磁共振波谱学(MR-spectroscopy)的可能性,强调通过这种方法可以对脑能量代谢进行完整而动态的研究,从而识别出比MRI形态学发现更敏感、更早出现的细胞损伤标志物。此外,该方法还能轻松评估脑血流量、药物治疗效果以及最终代谢异常对缺血进展的影响。