Departamento de Biología Celular y Ecología, Facultad de Biología, Universidad de Santiago de Compostela, 15782 Santiago de Compostela, Spain.
Parasitol Res. 2012 Apr;110(4):1573-8. doi: 10.1007/s00436-011-2664-1. Epub 2011 Oct 11.
Philasterides dicentrarchi is a histophagous scuticociliate that causes important losses in aquaculture. Several strains that differ in morphological, genetic and serological characteristics and virulence have been isolated from outbreaks of turbot scuticociliatosis. In the present study, seven isolates of the ciliate were exposed in vitro to formalin, hydrogen peroxide and resveratrol (a phytoalexin produced by plants) in order to evaluate the susceptibility of the isolates to the different compounds. The LD50 values for the three compounds tested varied widely among the isolates. The LD100 values were similar among isolates for formalin (25-30 ppm) and resveratrol (60-70 ppm) but were very different for hydrogen peroxide (25->80 ppm). The results indicate that there are many physiological differences among isolates and even among specimens of the same isolates, which must be taken into account in designing control programmes. The naturally occurring resveratrol may be a good alternative to other compounds for reducing the amounts of viable ciliates in water.
菲尔斯特里德斯迪肯塔奇是一种噬组织的盾纤毛虫，它会导致水产养殖中的重大损失。已经从大菱鲆盾纤毛虫病的爆发中分离出了几种在形态学、遗传学和血清学特征以及毒力方面存在差异的菌株。在本研究中，体外暴露了七种纤毛虫分离株于甲醛、过氧化氢和白藜芦醇（植物产生的一种植物抗毒素）中，以评估分离株对不同化合物的敏感性。三种测试化合物的 LD50 值在分离株之间差异很大。对于甲醛（25-30 ppm）和白藜芦醇（60-70 ppm），分离株的 LD100 值相似，但对于过氧化氢（25->80 ppm）则非常不同。结果表明，分离株之间甚至同一分离株的标本之间存在许多生理差异，在设计控制方案时必须考虑到这些差异。天然存在的白藜芦醇可能是替代其他化合物的一种很好的选择，可用于减少水中活纤毛虫的数量。
