Seize Maria Bandeira de Melo Paiva, Ianhez Mayra, Cestari Silmara da Costa Pereira
Federal University of Sao Paulo, Brasil.
An Bras Dermatol. 2011 Jul-Aug;86(4):663-8. doi: 10.1590/s0365-05962011000400006.
Although no scientific evidence has yet been published, it is widely understood that molluscum contagiosum tends to be more common and more intense in patients with atopic dermatitis. This lack of evidence led to the development of the present study.
To evaluate the prevalence of the association between atopic dermatitis and molluscum contagiosum; to evaluate whether molluscum contagiosum is more likely to be recurrent and/or disseminated in patients with atopic dermatitis and whether the occurrence of eczema surrounding the molluscum contagiosum lesions, pruritus and/or infection is more prevalent in these patients compared to patients without atopic dermatitis.
A total of 284 children of both sexes with a diagnosis of molluscum contagiosum and/or atopic dermatitis were evaluated.
Only 13.4% of the patients had both conditions. The number of anatomical areas affected by molluscum contagiosum and the occurrence of surrounding eczema and pruritus was greater in the patients who also had atopic dermatitis. There was no statistically significant difference in the frequency of secondary infection associated with the molluscum contagiosum lesions between the patients who had atopic dermatitis and those who did not.
The prevalence of atopic dermatitis associated with molluscum contagiosum was low. There was no statistically significant difference in the recurrence rates associated with molluscum contagiosum or in the number of lesions between the patients who had atopic dermatitis and those who did not. The number of anatomical areas affected by the molluscum contagiosum lesions and the presence of surrounding eczema and pruritus were higher in the patients with atopic dermatitis. There was no statistically significant difference in the occurrence of secondary bacterial infection between the groups with and without atopic dermatitis.
尽管尚无科学证据发表，但人们普遍认为，传染性软疣在特应性皮炎患者中往往更为常见且病情更为严重。正是由于缺乏这方面的证据，才开展了本研究。
评估特应性皮炎与传染性软疣之间关联的患病率；评估传染性软疣在特应性皮炎患者中是否更易复发和/或播散，以及与无特应性皮炎的患者相比，传染性软疣皮损周围湿疹、瘙痒和/或感染的发生率在这些患者中是否更高。
对总共284名诊断为传染性软疣和/或特应性皮炎的男女儿童进行了评估。
只有13.4%的患者同时患有这两种疾病。同时患有特应性皮炎的患者中，受传染性软疣影响的解剖部位数量以及周围湿疹和瘙痒的发生率更高。患有特应性皮炎的患者与未患特应性皮炎的患者相比，与传染性软疣皮损相关的继发感染频率无统计学显著差异。
与传染性软疣相关的特应性皮炎患病率较低。患有特应性皮炎的患者与未患特应性皮炎的患者相比，传染性软疣的复发率或皮损数量无统计学显著差异。传染性软疣皮损影响的解剖部位数量以及周围湿疹和瘙痒的发生率在特应性皮炎患者中更高。有特应性皮炎组和无特应性皮炎组之间继发细菌感染的发生率无统计学显著差异。
