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使用计算机化工作流程模拟评估全切片成像在大容量组织学实验室全面采用的可行性。

Using computerized workflow simulations to assess the feasibility of whole slide imaging full adoption in a high-volume histology laboratory.

机构信息

Department of Pathology, Massachusetts General Hospital, Boston, USA.

出版信息

Anal Cell Pathol (Amst). 2012;35(1):57-64. doi: 10.3233/ACP-2011-0034.

Abstract

BACKGROUND

Whole slide Imaging (WSI) has been touted by many as the future of pathology, with estimates of full adoption occurring sometime in the next 5 to 15 years. While WSI devices have become increasingly capable since their inception, there has been little consideration of how WSI will be implemented and subsequently affect the workflow of high volume histology laboratories.

METHODS

Histology workflow process data was collected from a high-volume histology laboratory (Massachusetts General Hospital) and a process model developed using business process management software. Computerized workflow simulations were performed and total histology process time evaluated under a number of different WSI conditions.

RESULTS

Total histology process time increased approximately 10-fold to 20-fold over baseline with the presence of one WSI robot in the histology workflow. Depending on the specifications of the WSI robot, anywhere from 9 to 14 WSI robots were required within the histology workflow to minimize the effects of WSI.

CONCLUSIONS

Placing a WSI robot into the current workflow of a high-volume histology laboratory with the intent of full adoption is not feasible. Implementing WSI without making significant changes to the current workflow of the histology laboratory would prove to be both disruptive and costly to surgical pathology.

摘要

背景

全玻片成像(WSI)被许多人誉为病理学的未来,预计在未来 5 到 15 年内全面采用。虽然自问世以来,WSI 设备的功能越来越强大,但很少有人考虑 WSI 将如何实施,以及随后如何影响大容量组织学实验室的工作流程。

方法

从一个大容量组织学实验室(马萨诸塞州综合医院)收集组织学工作流程数据,并使用业务流程管理软件开发流程模型。在许多不同的 WSI 条件下进行计算机化的工作流程模拟,并评估整个组织学过程的时间。

结果

在组织学工作流程中出现一个 WSI 机器人,整个组织学过程的时间大约增加了 10 到 20 倍。根据 WSI 机器人的规格,组织学工作流程中需要 9 到 14 个 WSI 机器人,以最小化 WSI 的影响。

结论

将 WSI 机器人放入大容量组织学实验室的当前工作流程中,意图全面采用是不可行的。如果不在组织学实验室的当前工作流程中进行重大更改就实施 WSI,将对手术病理学造成破坏性和昂贵的影响。

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