奎宁会导致可逆性高音调听力损失。
Quinine induces reversible high-tone hearing loss.
作者信息
Roche R J, Silamut K, Pukrittayakamee S, Looareesuwan S, Molunto P, Boonamrung S, White N J
机构信息
Nuffield Department of Clinical Medicine, University of Oxford, England.
出版信息
Br J Clin Pharmacol. 1990 Jun;29(6):780-2. doi: 10.1111/j.1365-2125.1990.tb03704.x.
Abstract
Serial audiometry was performed in ten patients receiving quinine treatment for acute falciparum malaria. Quinine reduced high tone auditory acuity in all patients, resulting in flattening of the audiograms. The effect was rapid in onset, usually unnoticed (although tinnitus was reported in seven patients), and resolved completely after treatment was completed.
摘要
对10名接受奎宁治疗急性恶性疟的患者进行了系列听力测定。奎宁降低了所有患者的高音听力敏锐度，导致听力图变平。这种效应起效迅速，通常未被注意到（尽管7名患者报告有耳鸣），且在治疗结束后完全消退。
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本文引用的文献
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