Wagg Adrian
Division of Geriatric Medicine, Department of Medicine, University of Alberta, Edmonton, AB.
Can Urol Assoc J. 2011 Oct;5(5 Suppl 2):S149-51. doi: 10.5489/cuaj.11188.
The prevalence of the overactive bladder (OAB) symptom complex increases with age. Older people also appear to experience more severe incontinence syndromes, including OAB, than their younger counterparts. Older patients are more likely than younger individuals to ask for medication for bladder problems and to require higher doses of medication. Conventional treatment for OAB with conservative and lifestyle measures in combination with antimuscarinic pharmacotherapy is effective in older people. Although there is a theoretical potential for cognitive impairment with antimuscarinic agents, the newer antimuscarinics are cognitively safe in cognitively intact older people.
膀胱过度活动症（OAB）症状复合体的患病率随年龄增长而增加。与年轻人群相比，老年人似乎也更容易出现包括OAB在内的更严重的失禁综合征。老年患者比年轻个体更有可能因膀胱问题寻求药物治疗，并且需要更高剂量的药物。采用保守和生活方式措施并结合抗毒蕈碱药物疗法对OAB进行的传统治疗在老年人中是有效的。尽管抗毒蕈碱药物理论上有导致认知障碍的可能性，但新型抗毒蕈碱药物在认知功能正常的老年人中在认知方面是安全的。
