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使用仅乙烯-乙烯醇共聚物(EVOH)Onyx 经颈动脉分叉处对副神经节瘤进行经皮栓塞的初步经验。

Preliminary experience with the percutaneous embolization of paragangliomas at the carotid bifurcation using only ethylene vinyl alcohol copolymer (EVOH) Onyx.

机构信息

University of Michigan Medical School, Ann Arbor, MI 48109-5030, USA.

出版信息

J Neurointerv Surg. 2012 Mar;4(2):125-9. doi: 10.1136/jnis.2010.003970. Epub 2011 Apr 20.

Abstract

BACKGROUND/PURPOSE: Carotid body paragangliomas are rare hypervascular lesions which may benefit from preoperative devascularization to reduce intraoperative blood loss. The optimal method for devascularization of these tumors is not known. Our purpose was to evaluate the extent of angiographic devascularization and intraoperative blood loss using only ethylene vinyl alcohol copolymer (EVOH) for percutaneous glomus tumor embolization.

METHODS

A consecutive series of seven paragangliomas located at the carotid bifurcation were treated with percutaneous embolization with EVOH as the sole embolic agent.

RESULTS

Complete devascularization of seven paragangliomas was achieved in all cases percutaneously with only EVOH. There were no complications. The average intraoperative blood loss was 55 ml (range 15-80 ml).

CONCLUSIONS

Our preliminary experience suggests that EVOH may offer a higher degree of devascularization when compared with other embolic agents. This may facilitate easier surgical resection with lower blood loss. EVOH seems to be safe when percutaneously injected as the sole embolic agent.

摘要

背景/目的:颈动脉体副神经节瘤是一种罕见的富血管性病变,术前血管阻断可能有助于减少术中出血。目前尚不清楚这些肿瘤血管阻断的最佳方法。我们的目的是评估仅使用乙烯-乙烯醇共聚物(EVOH)进行经皮球囊肿瘤栓塞术的血管造影阻断程度和术中出血量。

方法

连续 7 例位于颈动脉分叉处的副神经节瘤采用 EVOH 作为唯一栓塞剂进行经皮栓塞治疗。

结果

所有病例均通过仅使用 EVOH 经皮完全阻断 7 例副神经节瘤的血供。无并发症发生。术中平均出血量为 55ml(范围 15-80ml)。

结论

我们的初步经验表明,与其他栓塞剂相比,EVOH 可能提供更高程度的血管阻断。这可能有助于更轻松地进行手术切除,并减少出血量。当作为唯一栓塞剂经皮注射时,EVOH 似乎是安全的。

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