Neurosurgery Department, Faculty of Medicine, Cairo University, Egypt.
J Neurointerv Surg. 2011 Sep;3(3):288-92. doi: 10.1136/jnis.2010.002402. Epub 2010 Dec 8.
Although the standard treatment for lumbar disc herniation is lumbar microdiscectomy, nucleoplasty offers a new technique with encouraging results in well selected cases. Nucleoplasty is a minimally invasive technique that manages intradiscal herniation through energy based removal of part of the nucleus pulposus. The purpose of this study was to assess the safety and clinical outcome of the nucleoplasty procedure in well selected cases.
Coblation technology was used in 50 patients, who had radicular leg pain due to contained disc herniation or focal protrusion, from 2005 to 2008. Clinical outcome was assessed by the Visual Analog Scale and Oswestry Disability Index Questionnaire. Reduction in analgesic treatment was also recorded. The procedure was performed under local anesthesia.
The mean Visual Analog Scale score decreased from 8.2 to 1.3 at the 1 year evaluation (p=0.001). The Oswestry Disability Index Questionnaire decreased from 62.2 to 9.6 at the 1 year follow-up (p=0.001). Analgesic consumption was reduced or stopped in 90% of cases after 1 year. There was complete resolution of symptoms in 40 patients after 1 year. There were four patients who underwent conventional microdiscectomy. Five cases had postoperative discitis which cleared clinically and radiologically within 2 months without sequelae in four of them. One patient had to undergo operative instrumental fusion at the affected level.
Nucleoplasty does not require general anesthesia, offers less morbidity and shortens recovery time. Contained herniated disc or focal protrusion are the most important inclusion criteria. Hence this technique is a promising tool in well selected cases.
尽管腰椎间盘突出症的标准治疗方法是腰椎间盘显微切除术,但经皮髓核成形术在选择合适的病例中提供了一种新的技术,结果令人鼓舞。经皮髓核成形术是一种微创技术,通过基于能量的方法去除部分髓核来治疗椎间盘内突出。本研究的目的是评估经皮髓核成形术在选择合适的病例中的安全性和临床疗效。
从 2005 年到 2008 年,我们使用等离子消融技术治疗了 50 例因椎间盘内突出或局灶性突出引起神经根性腿痛的患者。临床疗效通过视觉模拟评分(VAS)和 Oswestry 残疾指数问卷(ODI)进行评估。还记录了镇痛治疗的减少情况。该手术在局部麻醉下进行。
在 1 年的评估中,VAS 评分从 8.2 降至 1.3(p=0.001)。ODI 问卷评分从 62.2 降至 9.6(p=0.001)。1 年后,90%的病例镇痛药物的使用减少或停止。1 年后,40 例患者症状完全缓解。有 4 例患者接受了常规的椎间盘切除术。5 例患者术后发生椎间盘炎,在 2 个月内临床和影像学均得到缓解,其中 4 例无后遗症。1 例患者需要在受累水平进行手术器械融合。
经皮髓核成形术不需要全身麻醉,具有较低的发病率,缩短了恢复时间。包含性椎间盘突出或局灶性突出是最重要的纳入标准。因此,对于选择合适的病例,该技术是一种很有前途的工具。