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等离子消融环缩成形术治疗椎间盘源性下腰痛的疗效:一项前瞻性观察研究。

Efficacy of coblation annuloplasty in discogenic low back pain: a prospective observational study.

作者信息

He Liangliang, Hu Xiangyu, Tang Yuanzhang, Li Xiuhua, Zheng Shuyue, Ni Jiaxiang

机构信息

From the Department of Pain Management, Xuanwu Hospital, Capital Medical University, No. 45 Changchun Street, Xicheng Zone, Beijing, China.

出版信息

Medicine (Baltimore). 2015 May;94(19):e846. doi: 10.1097/MD.0000000000000846.

DOI:10.1097/MD.0000000000000846
PMID:25984672
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4602569/
Abstract

In degenerative disc, the innervated outer annulus is confirmed to the major origin resulted in discogenic pain. To alleviate the discogenic pain, annuloplasty with electrothermal technology was proved to be effective, which mainly involves the thermal heating of the annulus to denature collagen fibers and denervate posterior annular nerve fibers. However, little is known that efficacy of annuloplasty with coblation technology in treating discogenic pain through directly interrupting nerves in outer annulus.The purpose of this study was to evaluate the clinical outcomes of coblation annuloplasty for the treatment of discogenic low back pain.In a clinical prospective observational study, 17 consecutive patients with discogenic low back pain underwent coblation annuloplasty under local anesthesia. Pain visual analogue scale (VAS) scores, patient responses stating significant (≥50%) pain relief, and modified MacNab criteria were adopted to evaluate the pain intensity, degree of pain relief, and functional status after 6 months of follow-up.The preoperative pain VAS score was 6.5 ± 0.8(95% confidence interval [CI] 6.1-6.9) and the pain VAS score decreased to 2.9 ± 1.6 (95% CI 2.1-3.8), 2.9 ± 1.7 (95% CI 2.1-3.8), 3.2 ± 1.6 (95% CI 2.4-4.1), 3.2 ± 1.7 (95% CI 2.4-4.2) at 1 week and 1, 3 and 6 month postoperatively, respectively. 12 (70.6%), 11 (64.7%), 10 (58.8%) and 10 (58.8%) of patients reported significant pain relief at 1 week and 1, 3 and 6 months postoperatively. At 1, 3, and 6 months postoperatively, the numbers of patients with "excellent" or "good" ratings were 13 (76.5%), 11 (64.7%), and 10 (58.8%) according to the modified MacNab criteria. No serious complications were observed.The finds show that coblation annuloplasty is an effective, safe, and less uncomfortable procedure in managing discogenic low back pain.

摘要

在退变椎间盘,已证实有神经支配的外环是椎间盘源性疼痛的主要来源。为缓解椎间盘源性疼痛,经证实,采用电热技术的纤维环成形术是有效的,该技术主要是对纤维环进行热加热以使胶原纤维变性并使后环神经纤维去神经支配。然而,关于采用低温等离子射频技术的纤维环成形术通过直接阻断外环神经来治疗椎间盘源性疼痛的疗效,人们了解甚少。本研究的目的是评估低温等离子射频纤维环成形术治疗椎间盘源性下腰痛的临床疗效。

在一项临床前瞻性观察研究中,17例连续性椎间盘源性下腰痛患者在局部麻醉下接受了低温等离子射频纤维环成形术。采用疼痛视觉模拟量表(VAS)评分、患者表示疼痛显著缓解(≥50%)的反应以及改良MacNab标准来评估随访6个月后的疼痛强度、疼痛缓解程度和功能状态。术前疼痛VAS评分为6.5±0.8(95%置信区间[CI]6.1 - 6.9),术后1周、1个月、3个月和6个月时疼痛VAS评分分别降至2.9±1.6(95%CI 2.1 - 3.8)、2.9±1.7(95%CI 2.1 - 3.8)、3.2±1.6(95%CI 2.4 - 4.1)、3.2±1.7(95%CI 2.4 - 4.2)。术后1周、1个月、3个月和6个月时,分别有12例(70.6%)、11例(64.7%)、10例(58.8%)和10例(58.8%)患者报告疼痛显著缓解。根据改良MacNab标准,术后1个月、3个月和6个月时,评定为“优”或“良”的患者数量分别为13例(76.5%)、11例(64.7%)和10例(58.8%)。未观察到严重并发症。

研究结果表明,低温等离子射频纤维环成形术是治疗椎间盘源性下腰痛的一种有效、安全且不适感较小的手术方法。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6344/4602569/a3bbf8096f4f/medi-94-e846-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6344/4602569/6784a5661950/medi-94-e846-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6344/4602569/498486c583bb/medi-94-e846-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6344/4602569/1d1bc5cc8c53/medi-94-e846-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6344/4602569/a3bbf8096f4f/medi-94-e846-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6344/4602569/6784a5661950/medi-94-e846-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6344/4602569/498486c583bb/medi-94-e846-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6344/4602569/1d1bc5cc8c53/medi-94-e846-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6344/4602569/a3bbf8096f4f/medi-94-e846-g005.jpg

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