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坏疽性脓皮病与全层烧伤:存在鉴别诊断问题吗?

Pyoderma Gangrenosum and Full-Thickness Burns: is there a Problem of Differential Diagnosis?

作者信息

Napoli B, D'Arpa N, Conte F

机构信息

Division of Plastic Surgery and Burns Therapy, ARNAS, Civic Hospital, Palermo, Italy.

出版信息

Ann Burns Fire Disasters. 2006 Jun 30;19(2):71-3.

PMID:21991027
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3188033/
Abstract

A case is presented of pyoderma gangrenosum, describing its characteristic features with particular reference to the phenomenon of pathergy, which considerably limits the surgical approach to the disease. After an account of the numerous skin ulcerations that have to be taken into consideration in order to make a differential diagnosis, it is noted that pyoderma gangrenosum can only on rare occasions be confused with a full-thickness granulating burn.

摘要

本文报告了一例坏疽性脓皮病病例,描述了其特征,特别提及同形反应现象,该现象极大地限制了对该病的手术治疗方法。在阐述了为进行鉴别诊断必须考虑的众多皮肤溃疡情况后,指出坏疽性脓皮病仅在极少数情况下会与全层肉芽形成性烧伤相混淆。

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Pyoderma Gangrenosum and Full-Thickness Burns: is there a Problem of Differential Diagnosis?坏疽性脓皮病与全层烧伤:存在鉴别诊断问题吗?
Ann Burns Fire Disasters. 2006 Jun 30;19(2):71-3.
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引用本文的文献

1
Severe pyoderma gangrenosum in association with a flame burn.伴有火焰烧伤的严重坏疽性脓皮病。
Case Reports Plast Surg Hand Surg. 2016 Mar 4;3(1):1-6. doi: 10.3109/23320885.2016.1149034. eCollection 2016.

本文引用的文献

1
Management of pyoderma gangrenosum--an update.坏疽性脓皮病的管理——最新进展
Indian J Dermatol Venereol Leprol. 2004 Nov-Dec;70(6):329-35.
2
Skin ulcers misdiagnosed as pyoderma gangrenosum.被误诊为坏疽性脓皮病的皮肤溃疡
N Engl J Med. 2002 Oct 31;347(18):1412-8. doi: 10.1056/NEJMoa013383.
3
Efficacy of the anti-TNF-alpha antibody infliximab against refractory systemic vasculitides: an open pilot study on 10 patients.
Rheumatology (Oxford). 2002 Oct;41(10):1126-32. doi: 10.1093/rheumatology/41.10.1126.
4
Ocular and extracutaneous involvement in pyoderma gangrenosum.坏疽性脓皮病的眼部及皮肤外受累情况。
Ophthalmology. 2002 Oct;109(10):1941-3. doi: 10.1016/s0161-6420(02)01165-x.
5
Pyoderma gangrensum--a complication of breast biopsy.坏疽性脓皮病——乳房活检的一种并发症。
Ulster Med J. 2002 May;71(1):66-7.
6
Treatment of recalcitrant ulcers in pyoderma gangrenosum with mycophenolate mofetil and autologous keratinocyte transplantation on a hyaluronic acid matrix.霉酚酸酯联合自体角质形成细胞在透明质酸基质上移植治疗坏疽性脓皮病顽固性溃疡
J Eur Acad Dermatol Venereol. 2000 May;14(3):187-90. doi: 10.1046/j.1468-3083.2000.00019.x.
7
Interleukin-8 overexpression is present in pyoderma gangrenosum ulcers and leads to ulcer formation in human skin xenografts.
Lab Invest. 2000 Apr;80(4):595-604. doi: 10.1038/labinvest.3780064.
8
Pyoderma gangrenosum.坏疽性脓皮病
Thorax. 2000 Apr;55(4):347. doi: 10.1136/thorax.55.4.345d.
9
Pyoderma gangrenosum with lung injury.伴有肺损伤的坏疽性脓皮病。
Thorax. 1999 Oct;54(10):953-5. doi: 10.1136/thx.54.10.953.
10
Acute pyoderma gangrenosum does not require surgical therapy.急性坏疽性脓皮病无需手术治疗。
Arch Fam Med. 1998 Jul-Aug;7(4):377-80. doi: 10.1001/archfami.7.4.377.