Skaf Ghassan S, Ayoub Chakib M, Domloj Nathalie T, Turbay Massud J, El-Zein Cherine, Hourani Mukbil H
Division of Neurosurgery, Department of Surgery, American University of Beirut Medical Center, P.O. Box 11-0236, Riad El Solh, Beirut 1107 2020, Lebanon.
Adv Orthop. 2011;2011:950576. doi: 10.4061/2011/950576. Epub 2011 Sep 7.
It has been previously suggested in the literature that with aging, degenerative changes as well as disc herniation start at the lower lumbar segments, with higher disc involvement observed in an ascending fashion in older age groups. We conducted a study to investigate this correlation between age and level of disc herniation, and to associate it with the magnitude of the Lumbar Lordotic Angle (LLA), as measured by Cobb's method. We followed retrospectively lumbosacral spine MRI's of 1419 patients with symptomatic disc herniation. Pearson's correlation was used in order to investigate the relationship between LLA, age, and level of disc herniation. Student's t-test was applied to assess gender differences. Young patients were found to have higher LLA (R = 0.44, P < 0.0001) and lower levels of disc herniation (R = 0.302, P < 0.0001), whereas older patients had higher level herniation in lower LLA group (mean LLA 28.6° and 25.4°) and lower level herniation in high LLA group (mean LLA 33.2°). We concluded that Lumbar lordotic Cobb's angle and age can be predictors of the level of lumbar disc herniation. This did not differ among men and women (R = 0.341, P < 0.0001).
先前文献中曾提出,随着年龄增长,退变改变以及椎间盘突出始于下腰椎节段,在老年人群中,椎间盘受累程度呈上升趋势,且高位节段受累更为明显。我们开展了一项研究,旨在调查年龄与椎间盘突出节段之间的这种相关性,并将其与通过Cobb法测量的腰椎前凸角(LLA)大小相关联。我们回顾性分析了1419例有症状椎间盘突出患者的腰骶部脊柱MRI。采用Pearson相关性分析来研究LLA、年龄和椎间盘突出节段之间的关系。应用Student's t检验来评估性别差异。结果发现,年轻患者的LLA较高(R = 0.44,P < 0.0001),椎间盘突出节段较低(R = 0.302,P < 0.0001),而老年患者在LLA较低组(平均LLA 28.6°和25.4°)的椎间盘突出节段较高,在LLA较高组(平均LLA 33.2°)的椎间盘突出节段较低。我们得出结论,腰椎前凸Cobb角和年龄可作为腰椎间盘突出节段的预测指标。男性和女性之间无差异(R = 0.341,P < 0.0001)。
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