Znati Kaoutar, Harmouch Taoufiq, Benlemlih Amal, Elfatemi Hinde, Chbani Laila, Amarti Afaf
Department of Pathology, Hassan II University Hospital, Fez, Morocco.
ISRN Gastroenterol. 2011;2011:943804. doi: 10.5402/2011/943804. Epub 2010 Nov 4.
Granular cell tumor (GCT) was first described by Abrikossof in 1926. This tumor is a benign neoplasm of unclear histogenesis that is generally believed to be of nerve sheath origin. GCT is not common and most often affects the tongue, skin, and soft tissue, although it may occur anywhere in the body. Gastrointestinal tract involvement, and especially that of the colon, is very rare. This usually benign tumor appears as a submucosal nodule, measuring less than 2 cm in diameter and is often found incidentally during colorectal examinations. We describe the case of a 27-year-old man with a GCT in the cecum that was detected after a screening colonoscopy. Endoscopic examination revealed a yellowish submucosal tumor, 0.7 cm in diameter. An endoscopic mucosal polypectomy was done for histological confirmation and treatment.
颗粒细胞瘤(GCT)于1926年由阿布里科索夫首次描述。这种肿瘤是一种组织发生不明的良性肿瘤,一般认为起源于神经鞘。GCT并不常见,最常累及舌头、皮肤和软组织,尽管它可能发生在身体的任何部位。胃肠道受累,尤其是结肠受累非常罕见。这种通常为良性的肿瘤表现为黏膜下结节,直径小于2厘米,常在结直肠检查时偶然发现。我们报告一例27岁男性患者,其在结肠镜筛查后发现盲肠有颗粒细胞瘤。内镜检查发现一个直径0.7厘米的淡黄色黏膜下肿瘤。为进行组织学确诊和治疗,实施了内镜下黏膜息肉切除术。