Rajagopal Meyyappa Devan, Gochhait Debasis, Shanmugan Dasarathan, Barwad Adarsh Wamanrao
Departments of Pathology, Jawaharlal Institute of Postgraduate Medical Education and Research, India.
Departments of Surgery, Jawaharlal Institute of Postgraduate Medical Education and Research, India.
Rare Tumors. 2017 Aug 29;9(2):6420. doi: 10.4081/rt.2017.6420. eCollection 2017 Jul 3.
Granular cell tumor (GCT) also known as Abrikossoff's tumor is a benign neoplasm that is usually seen in the fourth to sixth decades of life with slight female preponderance. It is most frequently seen in the oral cavity, skin, and subcutaneous tissue. Gastrointestinal tract involvement is uncommon, in which esophagus is the most commonly affected site. There are case reports of GCT in stomach, appendix, colon and rectum. In this article, we report a case of GCT involving cecum. The cell of origin in GCT is controversial. There are various pools of thoughts regarding its histogenesis, the details of which are reviewed in this article with emphasis on the diagnostic difficulties encountered in this tumor.
颗粒细胞瘤(GCT)也称为阿布里科索夫瘤,是一种良性肿瘤,通常见于40至60岁人群,女性略占优势。它最常见于口腔、皮肤和皮下组织。胃肠道受累并不常见,其中食管是最常受累的部位。有胃、阑尾、结肠和直肠颗粒细胞瘤的病例报告。在本文中,我们报告一例累及盲肠的颗粒细胞瘤。颗粒细胞瘤的起源细胞存在争议。关于其组织发生有各种观点,本文将对其细节进行综述,重点关注该肿瘤诊断中遇到的困难。