Feldman-Idov Yulie, Melamed Yehuda, Ore Liora
School of Public Health, Faculty of Social Welfare and Health Science, University of Haifa, Haifa, Israel.
Isr Med Assoc J. 2011 Sep;13(9):524-9.
Wounds of the lower extremities are a significant public health problem, being severe and costly to treat. Adjunctive treatment with hyperbaric oxygenation (HBOT) has proven to be a useful and cost-effective means of treating ischemic wounds, mainly in diabetic patients.
To describe patients with ischemic wounds treated at the Rambam and Elisha Hyperbaric Medical Center and their wound improvement following HBOT.
We conducted a retrospective cohort study of all patients (N = 385) treated in the center during 1998-2007 for ischemic non-healing wounds in the lower extremities.
The mean age of the patients was 61.9 years (SD 13.97). Most of them were diabetic (69.6%) and male (68.8%). Half of the subjects had a wound for more than 3 months prior to undergoing pre-HBOT transcutaneous oximetry (TcPO2) testing. Most of the wounds were classified as Wagner degree 1 or 2 (39.1% and 46.2% respectively). The median number of treatments per patient was 29. Only 63.1% of patients had continuous treatments. Approximately 20% of patients experienced mild side effects. An improvement occurred in 282 patients (77.7%) following HBOT: 15.2% fully recovered, 42.7% showed a significant improvement (and were expected to heal spontaneously), and 19.8% a slight improvement.
HBOT can benefit the treatment of non-healing ischemic wounds (especially when aided by pretreatment TcPO2 evaluation; data not shown). Our experience shows that this procedure is safe and contributes to wound healing.
下肢伤口是一个重大的公共卫生问题，治疗难度大且成本高。高压氧治疗（HBOT）作为辅助治疗手段，已被证明是治疗缺血性伤口的有效且具有成本效益的方法，主要用于糖尿病患者。
描述在兰巴姆和以利沙高压医学中心接受治疗的缺血性伤口患者及其在高压氧治疗后的伤口改善情况。
我们对1998年至2007年期间在该中心接受治疗的所有下肢缺血性不愈合伤口患者（N = 385）进行了一项回顾性队列研究。
患者的平均年龄为61.9岁（标准差13.97）。他们中的大多数是糖尿病患者（69.6%），男性居多（68.8%）。一半的受试者在接受高压氧治疗前经皮血氧饱和度（TcPO2）测试前伤口已存在超过3个月。大多数伤口被分类为瓦格纳1级或2级（分别为39.1%和46.2%）。每位患者治疗的中位数为29次。只有6
