Cornea Research Foundation of America, Indianapolis, IN 46260, USA.
Cornea. 2011 Dec;30(12):1382-6. doi: 10.1097/ICO.0b013e31821ddd25.
To evaluate patients' perspectives and outcomes of 2 different endothelial keratoplasty (EK) techniques performed in the fellow eyes of the same patients: Descemet stripping automated endothelial keratoplasty (DSAEK) and Descemet membrane endothelial keratoplasty (DMEK).
In this fellow eye, comparative, retrospective case series, the records of 15 patients who underwent DSAEK in 1 eye and DMEK in the fellow eye and completed at least 1 year of follow-up after the second procedure were reviewed. Visual outcomes and endothelial cell density were assessed. Patient satisfaction was evaluated using a subjective questionnaire.
At 12 months postoperatively, the mean best spectacle-corrected visual acuity (BSCVA) in the DMEK group was 0.07 logarithm of the minimum angle of resolution (20/24) and 0.20 logMAR (20/32) in the DSAEK group (P = 0.004). The majority of the patients (85%) perceived better visual quality in the DMEK eye. Furthermore, 62% preferred or would recommend DMEK to a friend or relative, whereas 15% preferred DSAEK and 23% reported no preference between the surgical procedures. The 1-year endothelial cell loss and the perceived discomfort level during the postoperative period were comparable for the 2 procedures.
The majority of the patients preferred or would recommend the DMEK procedure. Faster visual recovery and better final visual acuity were the main benefits of the DMEK technique.
评估 2 种不同的内皮角膜移植术（EK）在同一患者对侧眼的患者角度和结果：Descemet 撕囊自动化角膜内皮移植术（DSAEK）和 Descemet 膜内皮角膜移植术（DMEK）。
在这项对侧眼、比较性、回顾性病例系列研究中，回顾了 15 名患者的记录，这些患者 1 只眼接受了 DSAEK，对侧眼接受了 DMEK，并在第 2 次手术后至少随访了 1 年。评估了视力结果和内皮细胞密度。使用主观问卷评估患者满意度。
在术后 12 个月，DMEK 组的最佳矫正视力（BCVA）平均值为 0.07 对数最小角分辨率（20/24），DSAEK 组为 0.20 对数 MAR（20/32）（P=0.004）。大多数患者（85%）认为 DMEK 眼的视觉质量更好。此外，62%的患者更喜欢或会向朋友或亲戚推荐 DMEK，而 15%的患者更喜欢 DSAEK，23%的患者表示对这两种手术没有偏好。在术后期间，2 种手术的内皮细胞丢失和感知不适水平相当。
大多数患者更喜欢或会推荐 DMEK 手术。更快的视觉恢复和更好的最终视力是 DMEK 技术的主要优势。
