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[脑功能障碍的药物治疗。双氢麦角毒碱与银杏叶提取物的随机对照研究]

[Drug therapy of disorders of cerebral performance. Randomized comparative study of dihydroergotoxine and Ginkgo biloba extract].

作者信息

Gerhardt G, Rogalla K, Jaeger J

机构信息

Artz für Allgemeinmedizin, Psychotherapie, Wendelsheim.

出版信息

Fortschr Med. 1990 Jun 30;108(19):384-8.

PMID:2199358
Abstract

In a randomized trial lasting six weeks and involving 80 elderly patients with cerebrovascular disorders, the effectiveness and tolerance of dihydroergotoxine was compared with an extract of Ginkgo biloba. On the basis of psychometric tests and assessment scales, it was shown that treatment with either substance improved the condition of the patients. While, for the most part, intergroup comparison revealed no major statistically significant differences, such changes, affecting various parameters, were found during follow-up--more frequently within the dihydroergotoxine group than within the group treated with Ginkgo biloba extract.

摘要

在一项为期六周、涉及80名老年脑血管疾病患者的随机试验中,将双氢麦角毒碱的有效性和耐受性与银杏叶提取物进行了比较。根据心理测量测试和评估量表显示,两种药物治疗均改善了患者的病情。虽然在大多数情况下,组间比较没有发现重大的统计学显著差异,但在随访期间发现了影响各种参数的此类变化——在双氢麦角毒碱组中比在银杏叶提取物治疗组中更频繁。

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