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[脑功能障碍的药物治疗。双氢麦角毒碱与银杏叶提取物的随机对照研究]

[Drug therapy of disorders of cerebral performance. Randomized comparative study of dihydroergotoxine and Ginkgo biloba extract].

作者信息

Gerhardt G, Rogalla K, Jaeger J

机构信息

Artz für Allgemeinmedizin, Psychotherapie, Wendelsheim.

出版信息

Fortschr Med. 1990 Jun 30;108(19):384-8.

PMID:2199358
Abstract

In a randomized trial lasting six weeks and involving 80 elderly patients with cerebrovascular disorders, the effectiveness and tolerance of dihydroergotoxine was compared with an extract of Ginkgo biloba. On the basis of psychometric tests and assessment scales, it was shown that treatment with either substance improved the condition of the patients. While, for the most part, intergroup comparison revealed no major statistically significant differences, such changes, affecting various parameters, were found during follow-up--more frequently within the dihydroergotoxine group than within the group treated with Ginkgo biloba extract.

摘要

在一项为期六周、涉及80名老年脑血管疾病患者的随机试验中,将双氢麦角毒碱的有效性和耐受性与银杏叶提取物进行了比较。根据心理测量测试和评估量表显示,两种药物治疗均改善了患者的病情。虽然在大多数情况下,组间比较没有发现重大的统计学显著差异,但在随访期间发现了影响各种参数的此类变化——在双氢麦角毒碱组中比在银杏叶提取物治疗组中更频繁。

相似文献

1
[Drug therapy of disorders of cerebral performance. Randomized comparative study of dihydroergotoxine and Ginkgo biloba extract].[脑功能障碍的药物治疗。双氢麦角毒碱与银杏叶提取物的随机对照研究]
Fortschr Med. 1990 Jun 30;108(19):384-8.
2
Ginkgo biloba for dementia.
Med Lett Drugs Ther. 1998 Jun 19;40(1029):63-4.
3
[Ginkgo--myth and reality].[银杏——传说与现实]
Praxis (Bern 1994). 1995 Jan 3;84(1):1-6.
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The neuroprotective properties of the Ginkgo biloba leaf: a review of the possible relationship to platelet-activating factor (PAF).银杏叶的神经保护特性:关于其与血小板活化因子(PAF)可能关系的综述
J Ethnopharmacol. 1996 Mar;50(3):131-9. doi: 10.1016/0378-8741(96)01379-7.
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[Therapy of brain function disorders in the elderly. Proven therapeutic results with Ginkgo-biloba extract in degenerative and vascular dementia. Report of a symposium. Munich, 7 December 1990].[老年人脑功能障碍的治疗。银杏叶提取物治疗退行性和血管性痴呆的可靠治疗效果。研讨会报告。慕尼黑,1990年12月7日]
Fortschr Med Suppl. 1991;107:1-19.
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The bioavailability of ginkgolides in Ginkgo biloba extracts.
Planta Med. 1997 Dec;63(6):563-5. doi: 10.1055/s-2006-957768.
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[Ginkgo biloba in treatment of intermittent claudication. A systematic research based on controlled studies in the literature].[银杏叶治疗间歇性跛行:基于文献对照研究的系统综述]
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Ginkgo biloba.银杏
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[Superoxide dismutase activity of Ginkgo biloba extract].[银杏叶提取物的超氧化物歧化酶活性]
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[Personal experiences with naturopathy. Geriatrics between ginkgo and ginseng].[自然疗法的个人经历。银杏与人参之间的老年医学]
Fortschr Med. 1988 Sep 30;106(28):16, 18.

引用本文的文献

1
[External validity of clinical trials for treatment of dementia with ginkgo biloba extracts].[银杏叶提取物治疗痴呆症临床试验的外部效度]
Z Gerontol Geriatr. 2008 Aug;41(4):298-312. doi: 10.1007/s00391-008-0521-3. Epub 2008 Mar 11.
2
Complementary and alternative medicines in the treatment of dementia: an evidence-based review.补充和替代医学在痴呆治疗中的应用:一项基于证据的综述。
Drugs Aging. 2003;20(13):981-98. doi: 10.2165/00002512-200320130-00003.
3
Ginkgo biloba for cerebral insufficiency.银杏叶用于脑供血不足。
Br J Clin Pharmacol. 1992 Oct;34(4):352-8. doi: 10.1111/j.1365-2125.1992.tb05642.x.