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单部位腹腔镜手术治疗三级转诊中心复杂回结肠克罗恩病的早期经验。

Early experience with single-site laparoscopic surgery for complicated ileocolic Crohn's disease at a tertiary-referral center.

机构信息

Department of Surgery, The Pennsylvania State University, College of Medicine, M. S. Hershey Medical Center, 500 University Drive, H137, Hershey, PA 17033, USA.

出版信息

Surg Endosc. 2012 Mar;26(3):777-82. doi: 10.1007/s00464-011-1951-3. Epub 2011 Oct 13.

Abstract

BACKGROUND

The role of single-site laparoscopy (SSL) for the treatment of ileocolic Crohn's disease complicated by an abscess, a phlegmon, or fistulizing disease has not been thoroughly assessed.

METHODS

A prospectively maintained database of SSL surgeries performed between October 2010 and March 2011 was reviewed. Consecutive patients with ileocolic Crohn's disease complicated by a paracolic abscess, a phlegmon, or a fistula were included for analysis. Data recorded included demographic information, body mass index (BMI), estimated blood loss (EBL), length of surgery, rate of conversion to standard laparoscopic surgery or open surgery, length of hospital stay, and rate of complications.

RESULTS

A total of six patients were identified. Complications from Crohn's disease included four (66%) patients who developed a paracolic abscess that required drainage upon admission, one (16%) patient who developed a phlegmon, and one (16%) patient who developed an enterocutaneous fistula. Mean age of the study population was 25 years, with a mean BMI of 21 and a mean ASA score of 3. Five (83%) of the patients were immunosuppressed with high-dose steroids. Mean operative time was 160 min, with a median EBL of 60 mL. One patient required the insertion of an additional trocar, whereas there were no conversions to laparotomy. Four (66%) patients required diversion with a loop ileostomy. Median time to flatus was 1 day. All patients tolerated a diet on the day of surgery, with a median length of stay of 3 days. There were no deaths and no complications related to bleeding, organ injury, surgical site infections, or anastomotic leaks.

CONCLUSIONS

A single-site laparoscopic approach for complicated ileocolic Crohn's disease can be performed safely, with short lengths of hospital stay and with a low rate of complications. A multicenter study would be beneficial to validate these findings.

摘要

背景

单部位腹腔镜(SSL)治疗并发脓肿、脓性炎或瘘管病变的回结肠克罗恩病的作用尚未得到充分评估。

方法

回顾分析 2010 年 10 月至 2011 年 3 月间行 SSL 手术的前瞻性维护数据库。纳入分析并发结肠旁脓肿、脓性炎或瘘管的回结肠克罗恩病连续患者。记录的数据包括人口统计学信息、体重指数(BMI)、估计失血量(EBL)、手术时间、转换为标准腹腔镜手术或开放手术的比率、住院时间和并发症发生率。

结果

共确定了 6 例患者。克罗恩病的并发症包括 4 例(66%)患者入院时发生结肠旁脓肿需要引流,1 例(16%)患者发生脓性炎,1 例(16%)患者发生肠皮瘘。研究人群的平均年龄为 25 岁,平均 BMI 为 21,平均 ASA 评分为 3。5 例(83%)患者接受大剂量类固醇免疫抑制治疗。平均手术时间为 160 分钟,中位 EBL 为 60 毫升。1 例患者需要插入额外的 trocar,无中转开腹。4 例(66%)患者需要行回肠造口术以转流。中位排气时间为 1 天。所有患者在手术当天均可耐受饮食,中位住院时间为 3 天。无死亡,无与出血、器官损伤、手术部位感染或吻合口漏相关的并发症。

结论

对于并发的回结肠克罗恩病,单部位腹腔镜方法是安全可行的,具有较短的住院时间和较低的并发症发生率。多中心研究将有助于验证这些发现。

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