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本文引用的文献

1
Surgical management of Crohn's disease.克罗恩病的外科治疗。
Langenbecks Arch Surg. 2013 Jan;398(1):13-27. doi: 10.1007/s00423-012-0919-7. Epub 2012 Feb 21.
2
Laparoscopic surgery for recurrent Crohn's disease.腹腔镜手术治疗复发性克罗恩病。
Gastroenterol Res Pract. 2012;2012:381017. doi: 10.1155/2012/381017. Epub 2012 Jan 2.
3
Single-incision laparoscopic surgery for ileocolic resection in Crohn's disease.单孔腹腔镜手术在克罗恩病回肠结肠切除术中的应用。
Dis Colon Rectum. 2012 Feb;55(2):140-6. doi: 10.1097/DCR.0b013e31823d0e0d.
4
Early experience with single-site laparoscopic surgery for complicated ileocolic Crohn's disease at a tertiary-referral center.单部位腹腔镜手术治疗三级转诊中心复杂回结肠克罗恩病的早期经验。
Surg Endosc. 2012 Mar;26(3):777-82. doi: 10.1007/s00464-011-1951-3. Epub 2011 Oct 13.
5
Recent results of laparoscopic surgery in inflammatory bowel disease.腹腔镜手术在炎症性肠病中的近期结果。
World J Gastroenterol. 2011 Mar 7;17(9):1116-25. doi: 10.3748/wjg.v17.i9.1116.
6
Laparoscopic versus Open surgery for small bowel Crohn's disease.腹腔镜手术与开放手术治疗小肠克罗恩病的比较
Cochrane Database Syst Rev. 2011 Jan 19(1):CD006956. doi: 10.1002/14651858.CD006956.pub2.
7
Laparoscopic surgery for recurrent ileocolic Crohn's disease is as safe and effective as primary resection.腹腔镜手术治疗复发性回肠末端克罗恩病与初次手术同样安全有效。
Colorectal Dis. 2011 Dec;13(12):1413-6. doi: 10.1111/j.1463-1318.2010.02511.x.
8
Minimally invasive colectomy for Crohn's colitis: a single institution experience.克罗恩病性结肠炎的微创结肠切除术:单中心经验。
Inflamm Bowel Dis. 2010 Nov;16(11):1940-6. doi: 10.1002/ibd.21265.
9
The role of hand-assisted laparoscopic surgery in subtotal and total colectomy for Crohn's colitis.手助腹腔镜手术在克罗恩病结肠次全切除和全切除中的作用。
Surg Endosc. 2010 Nov;24(11):2713-7. doi: 10.1007/s00464-010-1031-0. Epub 2010 Apr 7.
10
Long-term outcomes following laparoscopically assisted versus open ileocolic resection for Crohn's disease.腹腔镜辅助与开腹回肠结肠切除术治疗克罗恩病的长期结果。
Br J Surg. 2010 Apr;97(4):563-8. doi: 10.1002/bjs.6918.

克罗恩病的腹腔镜手术:文献简要综述

Laparoscopic surgery for crohn disease: a brief review of the literature.

作者信息

Aarons Cary B

机构信息

Division of Colon and Rectal Surgery, University of Pennsylvania, Perelman School of Medicine, Philadelphia, Pennsylvania.

出版信息

Clin Colon Rectal Surg. 2013 Jun;26(2):122-7. doi: 10.1055/s-0033-1348051.

DOI:10.1055/s-0033-1348051
PMID:24436660
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3709945/
Abstract

Crohn disease remains a challenging clinical entity, both medically and surgically. It frequently presents in early adulthood and imposes a lifetime exposure to chronic inflammation that can affect the entire gastrointestinal tract. Although the mainstay of therapy is treatment with immunomodulating drugs, ∼70 to 90% of patients with Crohn disease will ultimately require surgery. Furthermore, there are high rates of symptomatic recurrences that may also require surgical intervention over time. There is no definitive cure for Crohn disease and surgery is reserved for failed medical therapy or the complications of the disease, namely, obstruction, septic complications (abscess, perforation), and fistulas. However, the robust inflammatory environment during these periods is not always conducive to a minimally invasive surgical approach. Despite the inherent technical challenges, the literature has increasingly shown that laparoscopy for Crohn disease, in the appropriate setting, is feasible and safe. In fact, it offers many advantages, which are particularly beneficial to this subset of patients, such as fewer wound complications, a shortened hospital course, less tissue trauma and subsequent adhesion formation, and earlier resumption of oral intake and bowel function.

摘要

克罗恩病在医学和外科治疗方面仍然是一个具有挑战性的临床实体。它通常在成年早期出现,使患者终生暴露于可影响整个胃肠道的慢性炎症中。尽管治疗的主要方法是使用免疫调节药物,但约70%至90%的克罗恩病患者最终仍需要手术治疗。此外,症状复发率很高,随着时间的推移可能也需要手术干预。克罗恩病无法彻底治愈,手术仅用于药物治疗失败或出现疾病并发症的情况,即梗阻、感染性并发症(脓肿、穿孔)和瘘管。然而,这些时期强烈的炎症环境并不总是有利于微创外科手术方法。尽管存在固有的技术挑战,但文献越来越多地表明,在适当的情况下,针对克罗恩病的腹腔镜手术是可行且安全的。事实上,它具有许多优势,对这类患者尤其有益,例如伤口并发症更少、住院时间缩短、组织创伤和随后的粘连形成更少,以及更早恢复经口进食和肠道功能。