卵母细胞受精方法对不明原因不孕症女性受精、妊娠及着床率的影响。
Effect of method of oocyte fertilization on fertilization, pregnancy and implantation rates in women with unexplained infertility.
作者信息
Check J H, Yuan W, Garberi-Levito M C, Swenson K, McMonagle K
机构信息
The University of Medicine and Dentistry of New Jersey, Robert Wood Johnson Medical School at Camden Cooper Hospital/University Medical Center, Department of Obstetrics and Gynecology Division of Reproductive Endocrinology & Infertility, Camden, NJ, USA.
出版信息
Clin Exp Obstet Gynecol. 2011;38(3):203-5.
PURPOSE
To determine if intracytoplasmic sperm injection (ICSI) offers an advantage over conventional oocyte insemination for women undergoing in vitro fertilization (IVF) and embryo transfer for unexplained infertility.
METHODS
A retrospective seven-year review of outcome following IVF with conventional insemination vs ICSI for the category of unexplained infertility. The decision on which method of insemination to use was made by the couple after hearing pros and cons with the consulting physician.
RESULTS
There was no difference in failed fertilization rates. However, the live delivered pregnancy rates were significantly higher for the group using conventional oocyte fertilization methods.
CONCLUSIONS
Because of increased embryologist time and therefore increased expense to the patient it makes more sense to first try conventional oocyte insemination over ICSI for unexplained infertility, especially since the former results in a significantly higher live delivery rate
目的
确定对于因不明原因不孕而接受体外受精（IVF）和胚胎移植的女性，卵胞浆内单精子注射（ICSI）是否比传统的卵母细胞授精具有优势。
方法
对因不明原因不孕接受IVF并采用传统授精与ICSI的患者进行为期七年的回顾性结局分析。夫妻在与咨询医生听取利弊后决定使用哪种授精方法。
结果
受精失败率没有差异。然而，使用传统卵母细胞受精方法的组活产妊娠率显著更高。
结论
由于胚胎学家花费的时间增加，因此患者费用增加，对于不明原因不孕，首先尝试传统卵母细胞授精而非ICSI更有意义，特别是因为前者的活产率显著更高。
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