一项配对对照研究，旨在评估子宫内膜息肉对体外受精-胚胎移植（IVF-ET）后妊娠率和着床率的影响。
Matched controlled study to evaluate the effect of endometrial polyps on pregnancy and implantation rates following in vitro fertilization-embryo transfer (IVF-ET).
作者信息
Check J H, Bostick-Smith C A, Choe J K, Amui J, Brasile D
机构信息
The University of Medicine and Dentistry of New Jersey, Robert Wood Johnson Medical School at Camden Cooper Hospital/University Medical Center, Department of Obstetrics and Gynecology Division of Reproductive Endocrinology & Infertility, Camden, NJ, USA.
出版信息
Clin Exp Obstet Gynecol. 2011;38(3):206-8.
PURPOSE
To determine if endometrial polyps negatively effect outcome following in vitro fertilization-embryo transfer (IVF-ET) and whether hysteroscopic resection improves pregnancy and implantation rates and/or decreases miscarriage rates.
METHODS
Retrospective study with two matched controlled groups (polyps vs no polyps) based on age and previous number of IVF failures. The polyp group was further stratified by whether polypectomy was performed or not.
RESULTS
There was no difference or even trend for lower pregnancy rates or higher miscarriage rates with the presence of endometrial polyps.
CONCLUSIONS
These data do not support the recommendation for hysteroscopic resection of endometrial polyps to aid conception rates.
目的
确定子宫内膜息肉是否会对体外受精-胚胎移植（IVF-ET）后的结局产生负面影响，以及宫腔镜切除是否能提高妊娠率和着床率和/或降低流产率。
方法
基于年龄和既往IVF失败次数进行回顾性研究，设立两个匹配的对照组（有息肉组与无息肉组）。息肉组再根据是否进行息肉切除术进一步分层。
结果
存在子宫内膜息肉时，妊娠率降低或流产率升高方面无差异甚至无趋势。
结论
这些数据不支持推荐进行宫腔镜切除子宫内膜息肉以提高受孕率。
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