Department of Reproductive Endocrinology, Zekai Tahir Burak Women’s Education and Research Hospital, Devlet Mah. Subay Loj. no: 19/11 Yenisehir, Ankara, Turkey.
Arch Gynecol Obstet. 2012 Jun;285(6):1753-7. doi: 10.1007/s00404-012-2238-1.
Endometrial polyp is the commenest pathology among the structural uterine abnormalities. In this study we compared the IVF outcomes of patients who underwent hysteroscopic endometrial polyp excision with respect to the time interval between the polyp resection and the subsequent IVF cycle.
A total of 60 patients were divided into two groups according to the time interval between the hysteroscopic polyp resection and the start of the following IVF cycle. Of these, 29 patients had the IVF procedures <6 months after the polyp resection, whereas in 31 patients comprising the comparison group, IVF interventions were done ≥ 6 months after the resection. The IVF outcomes were compared.
Differences in the mean number of retrieved oocytes, metaphase II (MII) oocytes and transferred embryos, ratios of MII oocytes, and G1, G2 and G3 embryo rates were insignificant between the groups (p > 0.05). The fertilization, implantation, and clinical pregnancy rates were also similar between the groups (p > 0.05).
IVF outcomes seem to be unrelated to the time interval between the hysteroscopic polyp resection and the initiation of the IVF; the success rates may not be superior if the treatment is started in the first few months postoperatively.
子宫内膜息肉是子宫结构异常中最常见的病理。本研究比较了宫腔镜子宫内膜息肉切除术后患者与随后的 IVF 周期之间的时间间隔对 IVF 结局的影响。
根据宫腔镜息肉切除术后与下一个 IVF 周期开始之间的时间间隔,将 60 例患者分为两组。其中 29 例患者在息肉切除后<6 个月进行 IVF 程序,而在 31 例比较组患者中,IVF 干预在切除后≥6 个月进行。比较 IVF 结果。
两组间获卵数、MII 卵数和移植胚胎数、MII 卵比例以及 G1、G2 和 G3 胚胎率的差异均无统计学意义(p>0.05)。两组间受精率、着床率和临床妊娠率也相似(p>0.05)。
宫腔镜息肉切除术后与 IVF 开始之间的时间间隔似乎与 IVF 结局无关;如果在术后头几个月开始治疗,成功率可能不会更高。