从 Scorzonera latifolia（Fisch. 和 Mey.）DC. 中提取的一种新三萜

A new triterpene from Scorzonera latifolia (Fisch. and Mey.) DC.

机构信息

Department of Pharmacognosy, Faculty of Pharmacy, Ankara University, 06100 Ankara, Turkey.

出版信息

Nat Prod Res. 2012;26(20):1892-7. doi: 10.1080/14786419.2011.625644. Epub 2011 Oct 13.

DOI:10.1080/14786419.2011.625644

PMID:21995805

Abstract

A novel triterpene 1 (3-β-hydroxy-fern-7-en-6-one-acetate) together with four known compounds, urs-12-en-11-one-3-acetyl (2), 3-β-hydroxy-fern-8-en-7-one-acetate (3), olean-12-en-11-one-3-acetyl (4) and leucodin (5) were obtained from the S. latifolia roots. All compounds were isolated from the n-hexane extract of S. latifolia roots using several chromatographic techniques. The structure of the isolated compounds was elucidated on the basis of (1)H-NMR, (13)C-NMR and 2D NMR data (HMBC, HMQC, COSY, TOCSY, NOESY, DEPT) as well as GC EITOF-HRMS.

摘要

从海南龙血树 S. latifolia 的根部中分离得到一个新的三萜化合物 1（3-β-羟基-蕨-7-烯-6-酮乙酸酯）和四个已知化合物，分别为：12-烯-11-酮-3-乙酰（2）、3-β-羟基-蕨-8-烯-7-酮乙酸酯（3）、12-烯-11-酮-3-乙酰（4）和亮氨酸二酮（5）。所有化合物均从海南龙血树 S. latifolia 的正己烷提取物中通过多种色谱技术分离得到。根据（1）H-NMR、（13）C-NMR 和 2D NMR 数据（HMBC、HMQC、COSY、TOCSY、NOESY、DEPT）以及 GC EITOF-HRMS 确定了分离化合物的结构。