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深板层角膜移植与飞秒激光辅助的穿透性角膜移植治疗圆锥角膜的疗效比较。

Outcomes of deep anterior lamellar keratoplasty versus intralase enabled penetrating keratoplasty in keratoconus.

机构信息

Department of Ophthalmology, Toronto Western Hospital, University of Toronto, Toronto, Ontario.

出版信息

Can J Ophthalmol. 2011 Oct;46(5):403-7. doi: 10.1016/j.jcjo.2011.07.003. Epub 2011 Aug 4.

Abstract

OBJECTIVE

To compare the visual and refractive outcomes after deep anterior lamellar keratoplasty (DALK) and intralase enabled keratoplasty (IEK) for keratoconus.

DESIGN

A retrospective comparative case series.

PARTICIPANTS

Eighteen eyes that underwent DALK and 18 that had IEK for keratoconus.

METHODS

Main outcome measures included preoperative and postoperative best spectacle corrected visual acuity (BSCVA), refraction, high-order aberrations (HOA), and complication rate were compared between the 2 groups after all suture removals.

RESULTS

Mean time to all suture removal was 11.91 months for the DALK and 6.7 months for the IEK. The mean logMAR BSCVA of patients in the DALK group was 0.28 (20/38) and 0.37 (20/46) in the IEK group (p < 0.211). The final sphere was -5.62 and -0.53 in the DALK and IEK groups, respectively (p < 0.973). There was statistically significant difference in the astigmatism between the 2 groups with mean manifest cylinder of 3.13 in the DALK group and 5.78 in the IEK group (p < 0.011).Total HOA (DALK 6.11 vs IEK 9.32, p < 0.036) and total spherical aberrations (DALK 0.44 vs IEK 0.71, p < 0.041) were both significantly higher in the IEK group. A total of 44.4% of eyes underwent astigmatic keratotomy after IEK compared to 5.6% of eyes in the DALK group (p < 0.018; odds ratio = 13.6 [1.48, 125.31]). Overall complication rates were similar for DALK and IEK groups.

CONCLUSIONS

BSCVA and complication rates are similar after DALK and IEK, but each technique has its advantage. IEK offered shorter time to suture removal whereas DALK offered lower postoperative astigmatism and HOA rates.

摘要

目的

比较深板层角膜移植术(DALK)和飞秒激光角膜内表面切削术(IEK)治疗圆锥角膜的视力和屈光结果。

设计

回顾性对比病例系列。

参与者

18 只接受 DALK 的眼和 18 只接受 IEK 的眼用于治疗圆锥角膜。

方法

主要观察指标包括两组患者所有缝线拆除后的术前和术后最佳矫正视力(BSCVA)、屈光度、高阶像差(HOA)和并发症发生率。

结果

DALK 组平均去除所有缝线的时间为 11.91 个月,IEK 组为 6.7 个月。DALK 组患者的平均 logMAR BSCVA 为 0.28(20/38),IEK 组为 0.37(20/46)(p<0.211)。DALK 组和 IEK 组的最终球镜度数分别为-5.62 和-0.53(p<0.973)。两组之间的散光存在统计学差异,DALK 组平均角膜散光为 3.13,IEK 组为 5.78(p<0.011)。IEK 组总 HOA(DALK 6.11 vs IEK 9.32,p<0.036)和总球差(DALK 0.44 vs IEK 0.71,p<0.041)均显著升高。IEK 组中有 44.4%的眼需要行散光性角膜切开术,而 DALK 组中仅有 5.6%的眼需要行该手术(p<0.018;优势比=13.6[1.48,125.31])。DALK 和 IEK 组的总体并发症发生率相似。

结论

DALK 和 IEK 术后的最佳矫正视力和并发症发生率相似,但每种技术都有其优势。IEK 可以更快地去除缝线,而 DALK 术后的散光和 HOA 发生率较低。

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