Espandar Ladan, Carlson Alan N
Duke Eye Center, Durham, NC 27710, USA.
J Ophthalmol. 2013;2013:894319. doi: 10.1155/2013/894319. Epub 2013 Oct 7.
The concept of lamellar keratoplasty (LK) is not new. However, newer forms of lamellar keratoplasty techniques have emerged in the last decade or so revolving around the concept of targeted replacement of diseased corneal layers. These include anterior lamellar keratoplasty (ALK) techniques that aim to selectively replace diseased corneal stroma and endothelial keratoplasty techniques aiming to replaced damaged endothelium in endothelial disorders. Recent improvements in surgical instruments and introduction of new techniques as well as inherent advantages such as preservation of globe integrity and decreased graft rejection have resulted in the reintroduction of LK as an acceptable alternative to conventional PK. In this review, indications, benefits, limitations, and outcomes of various anterior and posterior lamellar keratoplasty techniques are discussed.
板层角膜移植术(LK)的概念并不新鲜。然而,在过去十年左右的时间里,围绕着有针对性地替换病变角膜层的概念,出现了更新形式的板层角膜移植技术。这些技术包括旨在选择性替换病变角膜基质的前板层角膜移植术(ALK),以及旨在替换内皮疾病中受损内皮的内皮角膜移植术。手术器械的最新改进、新技术的引入以及诸如保持眼球完整性和降低移植排斥反应等固有优势,使得LK作为传统穿透性角膜移植术(PK)的一种可接受替代方法得以重新引入。在这篇综述中,将讨论各种前后板层角膜移植技术的适应症、益处、局限性和结果。